Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Effect of Nervus Cutaneous Femoris Lateralis-Blockade on Moderate Pain Responders After Total Hip Arthroplasty

Phase 4

Completed

Conditions: Pain, Postoperative
Ropivacaine
Therapeutic Use
Arthroplasty, Replacement, Hip

Interventions: Drug: Ropivacaine
Drug: Saline

First Posted Date: 2015-01-22

Last Posted Date: 2015-09-25

Lead Sponsor: Daniel Hägi-Pedersen

Target Recruit Count: 60

Registration Number: NCT02344264

Locations: 🇩🇰
Department of Anaesthesiology, Næstved, Danmark, Denmark

Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair

Not Applicable

Completed

Conditions: Pain, Postoperative

Interventions: Procedure: Pre-op percutaneous rectus sheath block
Procedure: Intra-operative rectus sheath block
Drug: Ropivacaine

First Posted Date: 2015-01-19

Last Posted Date: 2023-07-03

Lead Sponsor: Johns Hopkins All Children's Hospital

Target Recruit Count: 61

Registration Number: NCT02341144

Locations: 🇺🇸
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, United States

Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures

Not Applicable

Completed

Conditions: Hip Fracture

Interventions: Drug: Ropivacaine

First Posted Date: 2015-01-01

Last Posted Date: 2018-01-25

Lead Sponsor: Changi General Hospital

Target Recruit Count: 30

Registration Number: NCT02330302

Locations: 🇸🇬
Changi General Hospital, Singapore, Singapore

Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery

Not Applicable

Conditions: Colonic Neoplasms

Interventions: Drug: Fentanyl
Drug: Ropivacaine
Drug: Propofol
Drug: Isoflurane
Drug: Nitrous Oxide

First Posted Date: 2014-12-29

Last Posted Date: 2014-12-29

Lead Sponsor: Hillel Yaffe Medical Center

Target Recruit Count: 30

Registration Number: NCT02326727

Locations: 🇮🇱
Hillel Yaffe Medical Center, Hadera, Israel

The Study of Ropivacaine Median Effective Concentration in Ultrasound-guided Supraclavicular Brachial Plexus Block

Phase 4

Conditions: Anesthesia

Interventions: Drug: ropivacaine

First Posted Date: 2014-12-23

Last Posted Date: 2014-12-23

Lead Sponsor: Yu Shan

Target Recruit Count: 60

Registration Number: NCT02323282

Locations: 🇨🇳
Department of Anesthesiology,Sixth People's Hospital, Shanghai, Shanghai, China

Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication

Not Applicable

Completed

Conditions: Pain, Postoperative

Interventions: Drug: ropivacaine

First Posted Date: 2014-12-10

Last Posted Date: 2015-04-14

Lead Sponsor: Liberman, Eric, D.O.

Target Recruit Count: 220

Registration Number: NCT02314104

Locations: 🇺🇸
Saint Barnabas Medical Center, Livingston, New Jersey, United States

The Effects of Serratus Anterior Plane Block on Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery

Not Applicable

Completed

Conditions: Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery

Interventions: Drug: Ropivacaine
Drug: Normal Saline

First Posted Date: 2014-12-08

Last Posted Date: 2019-02-18

Lead Sponsor: Yonsei University

Target Recruit Count: 90

Registration Number: NCT02311517

Locations: 🇰🇷
Severance Hospital, Seoul, Korea, Republic of

Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty

Phase 4

Terminated

Conditions: Osteoarthritis of the Hip

Interventions: Drug: Ropivacaine
Drug: Saline

First Posted Date: 2014-11-24

Last Posted Date: 2017-02-09

Lead Sponsor: The Christ Hospital

Target Recruit Count: 72

Registration Number: NCT02299271

Locations: 🇺🇸
The Christ Hospital, Cincinnati, Ohio, United States

Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain

Not Applicable

Withdrawn

Conditions: Low Back Pain

Interventions: Device: ReLeaf catheter
Drug: Saline
Drug: Ropivacaine
Drug: Morphine
Drug: Oxycodone

First Posted Date: 2014-11-18

Last Posted Date: 2016-01-22

Lead Sponsor: Vital 5, LLC

Registration Number: NCT02293525

Effect of a Lateral Nerve of the Thigh Block on Postoperative Pain After Total Hip Replacement Surgery

Phase 4

Completed

Conditions: Pain, Postoperative
Anesthesia, Conduction
Arthroplasty, Replacement, Hip

Interventions: Drug: Placebo
Drug: Ropivacaine
Device: An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively

First Posted Date: 2014-11-13

Last Posted Date: 2014-11-13

Lead Sponsor: Daniel Hägi-Pedersen

Target Recruit Count: 100

Registration Number: NCT02289937

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy