Ropivacaine

Generic Name: Ropivacaine

Brand Names: Naropin

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₆N_₂O

CAS Number: 84057-95-4

Unique Ingredient Identifier: 7IO5LYA57N

Background: Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication: Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions: Acute Pain, Postoperative pain

Associated Therapies: Surgical anesthesia therapy

Clinical Trials

Horner's SD After Thoracic Epidural Block

Completed

Conditions: Horner's Syndrome

Interventions: Procedure: thoracic epidural anesthesia
Procedure: mastectomy
Drug: Ropivacaine
Drug: Propofol
Drug: Fentanyl

First Posted Date: 2014-05-05

Last Posted Date: 2014-05-05

Lead Sponsor: Soonchunhyang University Hospital

Target Recruit Count: 450

Registration Number: NCT02130739

Locations: 🇰🇷
Soonchunhyang University Seoul Hospital, Seoul, Korea, Republic of

Comparison of Continuous Femoral Nerve Block and Adductor Canal Block After Total Knee Replacement Therapy

Not Applicable

Completed

Conditions: Total Knee Arthroplasty
Total Knee Replacement
Adductor Canal Block
Femoral Nerve Block

Interventions: Drug: Ropivacaine

First Posted Date: 2014-04-29

Last Posted Date: 2015-01-26

Lead Sponsor: Philipps University Marburg Medical Center

Target Recruit Count: 44

Registration Number: NCT02125903

Locations: 🇩🇪
University of Marburg Department of Anaesthesia And Intensive Care Medicine, Marburg, Germany

Comparison of Two Kinds of Postoperative Analgesia After Amputation

Phase 4

Conditions: Complications
Pain

Interventions: Procedure: Intravenous analgesic
Procedure: Local analgesic
Drug: ropivacaine
Drug: flurbiprofen

First Posted Date: 2014-04-15

Last Posted Date: 2015-03-12

Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command

Target Recruit Count: 36

Registration Number: NCT02114463

Locations: 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China

Comparison of Three Kinds of Postoperative Analgesia After Total Knee Arthroplasty

Phase 4

Conditions: Pain
Complications

Interventions: Procedure: Local analgesic
Procedure: Nerve Block
Procedure: Intravenous analgesic
Drug: ropivacaine
Drug: opioid

First Posted Date: 2014-03-21

Last Posted Date: 2015-03-12

Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command

Target Recruit Count: 45

Registration Number: NCT02094339

Locations: 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China

Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone

Not Applicable

Withdrawn

Conditions: Caesarean Delivery

Interventions: Drug: TAP Block
Drug: Ropivacaine
Drug: Morphine
Drug: Acetaminophen

First Posted Date: 2014-03-19

Last Posted Date: 2016-08-05

Lead Sponsor: Dartmouth-Hitchcock Medical Center

Registration Number: NCT02091297

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
🇺🇸
Brigham & Women's Hospital, Boston, Massachusetts, United States

Does the Use of Ropivacaine Facilitates Cholecystectomy by Laparoscopy in Ambulatory Surgery?

Phase 4

Completed

Conditions: Cholecystectomy
Laparoscopy

Interventions: Drug: Ropivacaine

First Posted Date: 2014-03-13

Last Posted Date: 2015-05-19

Lead Sponsor: Centre Hospitalier Departemental Vendee

Target Recruit Count: 120

Registration Number: NCT02085902

Locations: 🇫🇷
Centre hospitalier départemental Vendée, La Roche sur Yon, France

Application of Combined Lumbar Plexus and Sciatic Nerve Block

Phase 4

Completed

Conditions: Anesthesia

Interventions: Procedure: Nerve block
Procedure: Combined spinal and epidural anesthesia
Drug: Ropivacaine
Drug: Bupivacaine

First Posted Date: 2014-03-12

Last Posted Date: 2014-09-11

Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command

Target Recruit Count: 34

Registration Number: NCT02084368

Locations: 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China

Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function

Not Applicable

Completed

Conditions: Paresis

Interventions: Drug: Bupivacaine
Drug: Ropivacaine

First Posted Date: 2014-02-11

Last Posted Date: 2014-11-25

Lead Sponsor: Anesthesiology WSU/DMC-NorthStar

Target Recruit Count: 39

Registration Number: NCT02059070

Locations: 🇺🇸
DMC Surgery Hospital, Madison Heights, Michigan, United States

A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures.

Phase 4

Terminated

Conditions: Supracondylar Fractures

Interventions: Drug: Ropivacaine
Drug: Fentanyl

First Posted Date: 2014-02-05

Last Posted Date: 2021-05-21

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 78

Registration Number: NCT02056288

Locations: 🇺🇸
Texas Children't Hospital, Houston, Texas, United States

Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia

Not Applicable

Completed

Conditions: Hip Fracture

Interventions: Procedure: Fascia iliaca compartment block
Drug: Fentanyl
Drug: ropivacaine

First Posted Date: 2014-01-16

Last Posted Date: 2014-01-16

Lead Sponsor: Asklepieion Voulas General Hospital

Target Recruit Count: 41

Registration Number: NCT02037633

Locations: 🇬🇷
Asklepieion Hospital of Voula, Athens, Attica, Greece

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