Acetaminophen

Generic Name: Acetaminophen

Brand Names: Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone

Drug Type: Small Molecule

Chemical Formula: C_₈H_₉NO_₂

CAS Number: 103-90-2

Unique Ingredient Identifier: 362O9ITL9D

Background: Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...

Indication: In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
...

Associated Conditions: Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain

Associated Therapies: Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation

Clinical Trials

Randomized Controlled Trial of Chiropractic Manipulation Versus Medical Therapy for Chronic Neck Pain

Not Applicable

Completed

Conditions: Neck Pain

First Posted Date: 2007-02-01

Last Posted Date: 2013-02-05

Lead Sponsor: University of Colorado, Denver

Target Recruit Count: 70

Registration Number: NCT00429624

Locations: 🇺🇸
University of Colorado Health Sciences Center, Denver, Colorado, United States

Study To Determine The Effects Of Doses Of Relacatib On The Metabolism Of Acetaminophen, Ibuprofen And Atorvastatin

Phase 1

Completed

Conditions: Osteoarthritis

Interventions: Drug: Relacatib
Drug: Ibuprofen
Drug: Acetaminophen
Drug: Atorvastatin

First Posted Date: 2006-12-13

Last Posted Date: 2017-10-04

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 32

Registration Number: NCT00411190

Locations: 🇧🇪
GSK Investigational Site, Liège, Belgium

Hepatic Function During and Following Three Days of Acetaminophen Dosing in Alcoholics

Phase 4

Completed

Conditions: Alcohol Related Disorders

First Posted Date: 2006-11-22

Last Posted Date: 2009-02-09

Lead Sponsor: Denver Health and Hospital Authority

Target Recruit Count: 420

Registration Number: NCT00402571

Locations: 🇺🇸
Denver CARES, Denver, Colorado, United States
🇺🇸
Recovery Centers of King County, Seattle, Washington, United States

Effects of Therapeutic Doses of Acetaminophen in Moderate Drinkers

Phase 4

Completed

Conditions: Moderate Alcohol Consumption (1-3 Drinks Per Day)

First Posted Date: 2006-11-17

Last Posted Date: 2024-07-08

Lead Sponsor: Denver Health and Hospital Authority

Target Recruit Count: 150

Registration Number: NCT00400621

A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus

Phase 3

Terminated

Conditions: Lupus Erythematosus, Systemic

Interventions: Drug: Rituximab
Drug: Methylprednisolone
Drug: Acetaminophen
Drug: Diphenhydramine

First Posted Date: 2006-09-28

Last Posted Date: 2017-08-01

Lead Sponsor: Genentech, Inc.

Target Recruit Count: 31

Registration Number: NCT00381810

Locations: 🇺🇸
Arizona Arthritis & Rheumatology Research, Pllc, Paradise Valley, Arizona, United States
🇺🇸
Eden Medical Center San Leandro Hospital, San Leandro, California, United States
🇺🇸
Intermountain Research Center, Boise, Idaho, United States

and more 8 locations