Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-

The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose Ketamine

First Posted Date
2023-04-25
Last Posted Date
2023-04-25
Lead Sponsor
Al-Azhar University
Target Recruit Count
80
Registration Number
NCT05828199
Locations
🇪🇬

Faculty of Medicine, Al-Azhar University, Cairo, Egypt

The Effect of Dexmedetomidine, Melatonin and Pregabalin

First Posted Date
2023-04-25
Last Posted Date
2023-04-25
Lead Sponsor
Egymedicalpedia
Target Recruit Count
120
Registration Number
NCT05829148
Locations
🇪🇬

Al-Azhar University hospitals, Cairo, Egypt

Efficacy of Adding Dexmedetomidine in Ultrasound-guided Intermediate Cervical Plexus Block for Thyroidectomy Surgery

First Posted Date
2023-04-18
Last Posted Date
2024-04-05
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
60
Registration Number
NCT05814744
Locations
🇪🇬

National Cancer Institue, Cairo, Fom El Khalig, Egypt

Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo

First Posted Date
2023-03-27
Last Posted Date
2023-04-06
Lead Sponsor
University of Southern Denmark
Target Recruit Count
220
Registration Number
NCT05785689
Locations
🇩🇰

Odense University Hospital, Odense, Denmark

Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome

First Posted Date
2023-03-21
Last Posted Date
2024-10-09
Lead Sponsor
Ain Shams University
Target Recruit Count
50
Registration Number
NCT05778305
Locations
🇪🇬

Ain Shams University, Cairo, Abassia, Egypt

COMPARISON OF DEXMEDETOMIDINE AND REMIFENTANIL FOR POSTOPERATIVE PAIN IN TRANSPHENOIDAL Pituitary SURGERY

First Posted Date
2023-03-16
Last Posted Date
2023-03-16
Lead Sponsor
Kocaeli University
Target Recruit Count
84
Registration Number
NCT05772832
Locations
🇹🇷

University of Kocaeli, Kocaeli, Izmit, Turkey

Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery

First Posted Date
2023-03-13
Last Posted Date
2023-03-13
Lead Sponsor
nada moahmed aboelrouse
Target Recruit Count
50
Registration Number
NCT05766436
Locations
🇪🇬

Ain shams university hospital, Cairo, Abbasia, Egypt

A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-03-02
Last Posted Date
2023-03-02
Lead Sponsor
Sohag University
Target Recruit Count
100
Registration Number
NCT05751304
Locations
🇪🇬

Sohag University Hospital, Sohag, Egypt

Analgesic Additives to Epidural Bupivacaine in Normal Labor

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-02-27
Last Posted Date
2023-02-27
Lead Sponsor
Assiut University
Target Recruit Count
69
Registration Number
NCT05746351

Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-02-24
Last Posted Date
2023-02-24
Lead Sponsor
Assiut University
Target Recruit Count
150
Registration Number
NCT05743725
Locations
🇪🇬

Faculty of Medicine, Assiut University, Assiut, Egypt

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