Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Comparing TIVA Using Propofol or Dexmedetomidine Versus Sevoflurane During Anaesthesia of Children Undergoing Bone-Marrow Aspiration

First Posted Date
2022-12-05
Last Posted Date
2022-12-05
Lead Sponsor
Alexandria University
Target Recruit Count
60
Registration Number
NCT05636566
Locations
🇪🇬

Alexandria University Faculty of Medicin, Alexandria, Egypt

Dexmedetomidine in Reducing Incidence of Emergence Agitation After Nasal Surgery

Phase 3
Completed
Conditions
Postoperative Delirium
Interventions
Drug: Dexmedetomidine
First Posted Date
2022-12-02
Last Posted Date
2023-04-04
Lead Sponsor
Security Forces Hospital
Target Recruit Count
42
Registration Number
NCT05634148
Locations
🇸🇦

Security Forces Hospital, Riyadh, Saudi Arabia

95% Effective Dose(ED95) of Remimazolam During Dexmedetomidine Pretreatment

First Posted Date
2022-11-30
Last Posted Date
2023-03-14
Lead Sponsor
Shiyou Wei
Target Recruit Count
115
Registration Number
NCT05631028
Locations
🇨🇳

Shanghai Pulmonary Hospital, Shanghai, Shanghai, China

Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

Phase 4
Completed
Conditions
Anesthesia
Interventions
Drug: Dexmedetomidine
Drug: Gabapentin
First Posted Date
2022-11-25
Last Posted Date
2023-08-30
Lead Sponsor
Ain Shams University
Target Recruit Count
153
Registration Number
NCT05626998
Locations
🇪🇬

faculty of medicine, Ain Shams University, Cairo, Egypt

Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome

Not Applicable
Recruiting
Conditions
Carpal Tunnel Syndrome
Interventions
Drug: Dexmedetomidine
Drug: Triamcinolone
First Posted Date
2022-11-22
Last Posted Date
2023-10-31
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT05624866
Locations
🇪🇬

Assiut Universit Hospital, Assiut, Egypt

Dexmedetomidine Reduce Postoperative Pain of C-section

Phase 4
Recruiting
Conditions
Pain, Postoperative
Interventions
Drug: Placebo
Drug: Dexmedetomidine
First Posted Date
2022-11-18
Last Posted Date
2022-11-18
Lead Sponsor
First People's Hospital of Chenzhou
Target Recruit Count
80
Registration Number
NCT05622656
Locations
🇨🇳

Zhiming Zhang, Chenzhou, Hunan, China

Oral Dexmedetomidine in Pediatric MRI

Phase 1
Not yet recruiting
Conditions
Anesthesia
Interventions
Drug: General anesthetic
Drug: Dexmedetomidine
First Posted Date
2022-11-17
Last Posted Date
2024-07-31
Lead Sponsor
Children's Mercy Hospital Kansas City
Target Recruit Count
120
Registration Number
NCT05619627
Locations
🇺🇸

Children's Mercy Hospital, Kansas City, Missouri, United States

The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)

First Posted Date
2022-11-14
Last Posted Date
2023-02-15
Lead Sponsor
Ciusss de L'Est de l'Île de Montréal
Target Recruit Count
84
Registration Number
NCT05615194
Locations
🇨🇦

Hôpital Maisonneuve-Rosemont, CIUSSS de l'Est de l'Ile de Montréal, Montréal, Quebec, Canada

Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia

Phase 3
Recruiting
Conditions
Insomnia
Interventions
Drug: Zolpidem
Drug: Dexmedetomidine
Other: Placebo
First Posted Date
2022-11-14
Last Posted Date
2022-11-14
Lead Sponsor
The University of Hong Kong
Target Recruit Count
20
Registration Number
NCT05615727
Locations
🇨🇳

HKU Li Ka Shing Faculty of Medicine, Hong Kong, Guangdong, China

Optic Nerve Sheath Diameter in Pre-Eclamptic Parturient Receiving Magnesium Sulfate Combined with Dexmedetomidine

First Posted Date
2022-11-09
Last Posted Date
2024-12-19
Lead Sponsor
Benha University
Target Recruit Count
50
Registration Number
NCT05610774
Locations
🇪🇬

Samar Rafik Amin, Banhā, Qalubia, Egypt

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