Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Post-Marketing Clinical Study to Assess Efficacy and Safety of Dexmedetomidine in Post-Operative Patients
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2017-03-20
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 85
- Registration Number
- NCT00318955
- Locations
- 🇯🇵
Kinki University Hospital, Osaka-Sayama-Shi, Osaka, Japan
🇯🇵Osaka University Hospital, Suita, Osaka, Japan
🇯🇵Nippon Medical School Hospital, Bunkyo-ku, Tokyo, Japan
Dexmedetomidine for Continuous Sedation
- Conditions
- First Posted Date
- 2005-09-27
- Last Posted Date
- 2006-11-14
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 900
- Registration Number
- NCT00226785
- Locations
- 🇫🇮
Helsinki University Hospital, Helsinki, Finland
🇨🇭Inselspital, Bern, Switzerland
🇫🇮Kuopio University Hospital, Kuopio, Finland
Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids
- Conditions
- Interventions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2016-01-14
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 40
- Registration Number
- NCT00205712
- Locations
- 🇺🇸
Washington University School of Medicine, Psychiatry Dept., St. Louis, Missouri, United States
MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status
- First Posted Date
- 2004-11-02
- Last Posted Date
- 2018-09-11
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 100
- Registration Number
- NCT00095251
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Drug Development Updates
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