Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study
- Conditions
- First Posted Date
- 2006-11-20
- Last Posted Date
- 2007-11-04
- Lead Sponsor
- The Cooper Health System
- Target Recruit Count
- 12
- Registration Number
- NCT00401206
- Locations
- 🇺🇸
Cooper University Hospital, Camden, New Jersey, United States
A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation During Monitored Anesthesia Care (MAC)
- Conditions
- Interventions
- First Posted Date
- 2006-11-14
- Last Posted Date
- 2015-07-23
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 326
- Registration Number
- NCT00398827
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
🇺🇸The Ohio State University, Columbus, Ohio, United States
🇺🇸University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Bariatric Dose-ranging Study With Dexmedetomidine
- Conditions
- First Posted Date
- 2006-08-15
- Last Posted Date
- 2019-01-16
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Registration Number
- NCT00363935
- Locations
- 🇺🇸
The University of Texas Southwestern MedicalCenter at Dallas, Dallas, Texas, United States
Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium
- Conditions
- Interventions
- First Posted Date
- 2006-07-12
- Last Posted Date
- 2017-06-09
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 53
- Registration Number
- NCT00351299
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Dexmedetomidine vs. Remifentanil for Sedation During AFI
- Conditions
- First Posted Date
- 2006-07-06
- Last Posted Date
- 2016-03-23
- Target Recruit Count
- 30
- Registration Number
- NCT00349245
- Locations
- 🇺🇸
Memorial Hermann Hospital, Houston, Texas, United States
Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
- Conditions
- Interventions
- First Posted Date
- 2006-06-28
- Last Posted Date
- 2016-02-08
- Lead Sponsor
- Baylor Research Institute
- Target Recruit Count
- 38
- Registration Number
- NCT00345384
- Locations
- 🇺🇸
Baylor University Medical Center - Department of Anesthesiology, Dallas, Texas, United States
Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine
- Conditions
- First Posted Date
- 2006-06-20
- Last Posted Date
- 2019-01-16
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Registration Number
- NCT00338546
- Locations
- 🇺🇸
Univ of Texas Southwestern Medical Center, Dallas, Texas, United States
The Effects of Dexmedetomidine and Remifentanil on Carotid Patients
- Conditions
- Interventions
- First Posted Date
- 2006-06-12
- Last Posted Date
- 2017-08-11
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 142
- Registration Number
- NCT00335972
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Dexmed/Buspirone Synergism on Shivering
- Conditions
- Interventions
- First Posted Date
- 2006-06-07
- Last Posted Date
- 2016-06-29
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 8
- Registration Number
- NCT00334360
- Locations
- 🇺🇸
Outcomes Research Institute, University of Louisville, Louisville, Kentucky, United States
Effect of Dexmedetomidine Upon Sleep Postoperatively
- Conditions
- First Posted Date
- 2006-06-06
- Last Posted Date
- 2014-07-14
- Lead Sponsor
- Duke University
- Registration Number
- NCT00333632
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.