Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy
- First Posted Date
- 2008-04-08
- Last Posted Date
- 2021-03-23
- Lead Sponsor
- Children's National Research Institute
- Target Recruit Count
- 101
- Registration Number
- NCT00654511
- Locations
- 🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States
The Effect of Sedation on Eye Movements
- Conditions
- Interventions
- First Posted Date
- 2008-03-28
- Last Posted Date
- 2017-05-19
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 65
- Registration Number
- NCT00646646
- Locations
- 🇺🇸
General Clinical Research Center, Birmingham, Alabama, United States
Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
- Conditions
- Interventions
- First Posted Date
- 2008-03-24
- Last Posted Date
- 2011-11-22
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Target Recruit Count
- 10
- Registration Number
- NCT00641563
- Locations
- 🇨🇭
Departement of Intensive Care Medicine - University Hospital Bern - Inselspital, Bern, Switzerland
Understanding Dexmedetomidine in Neonates After Open Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2007-12-19
- Last Posted Date
- 2013-04-18
- Lead Sponsor
- Athena Zuppa
- Target Recruit Count
- 30
- Registration Number
- NCT00576381
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2007-12-13
- Last Posted Date
- 2013-04-09
- Lead Sponsor
- Athena Zuppa
- Target Recruit Count
- 56
- Registration Number
- NCT00573066
Precedex Versus Propofol-Awakening for Reducing Brain Injury Expansion
- Conditions
- Interventions
- First Posted Date
- 2007-10-02
- Last Posted Date
- 2013-04-11
- Lead Sponsor
- Carmelo Graffagnino
- Target Recruit Count
- 8
- Registration Number
- NCT00538616
- Locations
- 🇺🇸
Duke University, Durham, North Carolina, United States
Long-term Clinical Study Evaluating the Safety and Efficacy of Dexmedetomidine in ICU Subjects
- First Posted Date
- 2007-09-10
- Last Posted Date
- 2015-06-30
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 80
- Registration Number
- NCT00526760
- Locations
- 🇯🇵
Hyogo Medical University Hospital, Nishinomiya-City, Hyogo, Japan
🇯🇵Nippon Medical School Hospital, Bunkyo-ku, Tokyo, Japan
🇯🇵Keio University Hospital, Sinjuku-ku, Tokyo, Japan
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
- Conditions
- Interventions
- First Posted Date
- 2007-07-25
- Last Posted Date
- 2013-01-24
- Lead Sponsor
- Austin Health
- Target Recruit Count
- 20
- Registration Number
- NCT00505804
Influence of Dexmedetomidine on the Evoked Potentials During Spine Surgery
- First Posted Date
- 2007-07-02
- Last Posted Date
- 2012-09-14
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 40
- Registration Number
- NCT00494832
- Locations
- 🇺🇸
Harborview Medical Center, Seattle, Washington, United States
🇺🇸University of Washington Medical Center, Seattle, Washington, United States
Dexmedetomidine Versus Midazolam for Continuous Sedation in the Intensive Care Unit (ICU)
- Conditions
- Interventions
- First Posted Date
- 2007-06-01
- Last Posted Date
- 2012-05-07
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 501
- Registration Number
- NCT00481312
- Locations
- 🇧🇪
ULB Erasme, Route de Lennik, Brussels, Belgium
🇧🇪UZ Brussel, Intensive Care Dept. Laarbeeklaan 101, Brussels, Belgium
🇧🇪Universitaer Ziekenhuis Gent, Intensieve Zorgen, De Pintelaan 185, Gent, Belgium
Drug Development Updates
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