Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Intranasal Dexmedetomidine for Severe Dental Anxiety: a Randomized Trial
- First Posted Date
- 2022-08-15
- Last Posted Date
- 2022-11-02
- Target Recruit Count
- 30
- Registration Number
- NCT05500261
Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia
- Conditions
- Interventions
- First Posted Date
- 2022-08-04
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Grace Lim, MD, MS
- Target Recruit Count
- 88
- Registration Number
- NCT05487196
- Locations
- 🇺🇸
UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States
Neuroprotective Effect of Dexomitomidine
- Conditions
- Interventions
- First Posted Date
- 2022-08-04
- Last Posted Date
- 2022-08-04
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 80
- Registration Number
- NCT05487742
- Locations
- 🇪🇬
Faculty of Medicine Tanta University, Tanta, Egypt
Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs.
- Conditions
- Interventions
- First Posted Date
- 2022-08-03
- Last Posted Date
- 2023-04-27
- Target Recruit Count
- 430
- Registration Number
- NCT05485519
- Locations
- 🇸🇦
King Abdullah Specialist Children Hospital (KASCH), Riyadh, Saudi Arabia
Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial
- First Posted Date
- 2022-08-02
- Last Posted Date
- 2022-08-02
- Lead Sponsor
- Aga Khan University Hospital, Pakistan
- Target Recruit Count
- 60
- Registration Number
- NCT05484648
Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
- First Posted Date
- 2022-08-01
- Last Posted Date
- 2022-08-01
- Lead Sponsor
- Hamdard University
- Target Recruit Count
- 104
- Registration Number
- NCT05481281
Bupivacaine Alone vs Bupivacaine and Dexmed in Cesarean Deliveries
- First Posted Date
- 2022-07-21
- Last Posted Date
- 2022-07-21
- Lead Sponsor
- KRL Hospital, Islamabad
- Target Recruit Count
- 100
- Registration Number
- NCT05469529
- Locations
- 🇵🇰
KRL Hospital, Islamabad, Pakistan
Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients
- Conditions
- Interventions
- First Posted Date
- 2022-07-20
- Last Posted Date
- 2024-05-07
- Target Recruit Count
- 100
- Registration Number
- NCT05466708
- Locations
- 🇨🇳
The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China
Vasopressor Requirements Depends on Sedation Strategy
- First Posted Date
- 2022-07-11
- Last Posted Date
- 2022-07-12
- Lead Sponsor
- Anesthesia Research Group UA
- Target Recruit Count
- 356
- Registration Number
- NCT05451381
- Locations
- 🇺🇦
Cardiosurgery departments with intensive care block, Kyiv, Ukraine
Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-07-11
- Last Posted Date
- 2022-07-11
- Lead Sponsor
- Anesthesia Research Group UA
- Target Recruit Count
- 356
- Registration Number
- NCT05451121
- Locations
- 🇺🇦
Anesthesia department Medical Network Dobrobut, Kyiv, Ukraine
Drug Development Updates
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