Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Anxiolysis for Laceration Repair in Children
- Conditions
- Interventions
- First Posted Date
- 2022-05-20
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Lawson Health Research Institute
- Target Recruit Count
- 300
- Registration Number
- NCT05383495
- Locations
- 🇨🇦
London Health Sciences Centre, London, Ontario, Canada
EC50 of Dexmedetomidine in Deep Brain Stimulation Implantation of Patients With Parkinson's Disease
- First Posted Date
- 2022-05-17
- Last Posted Date
- 2022-06-21
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT05376761
- Locations
- 🇨🇳
Beijing Tiantan hospital, Beijing, Beijing, China
To Evaluate if Dexmedetomidine Infusion Provides Renal Protection in Patients Undergoing Coronary Artery Bypass Graft
- First Posted Date
- 2022-05-16
- Last Posted Date
- 2022-05-16
- Target Recruit Count
- 60
- Registration Number
- NCT05375188
- Locations
- 🇵🇰
NICVD Karachi, Karachi, Sindh, Pakistan
Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-05-05
- Last Posted Date
- 2022-09-02
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 70
- Registration Number
- NCT05361642
- Locations
- 🇪🇬
Moustafa Rakha, Cairo, Egypt
Effect of Two Different Doses of Intrathecal Dexmedetomidine as Adjuvant in Elderly Patients Undergoing HoLEP
- Conditions
- Interventions
- First Posted Date
- 2022-04-28
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 70
- Registration Number
- NCT05351489
- Locations
- 🇪🇬
Urology and nephrology center, Mansoura, Dakahlia, Egypt
Dexmedetomidine Versus Nalbuphine as an Adjuvant to Intrathecal Bupivacaine
- First Posted Date
- 2022-04-26
- Last Posted Date
- 2024-03-15
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 60
- Registration Number
- NCT05347173
- Locations
- 🇪🇬
Mansoura University-Emergency hospital-ICU, El Dakahlia, Mansoura, Egypt
A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2022-04-25
- Last Posted Date
- 2022-04-25
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 23
- Registration Number
- NCT05342870
Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter
- Conditions
- Interventions
- First Posted Date
- 2022-04-22
- Last Posted Date
- 2022-04-22
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 108
- Registration Number
- NCT05340803
Comparison of Dexmedetomidine and Midazolam for Intra-op Sedation in TIVA in Children Undergoing Inguinal Hernia Repair
- First Posted Date
- 2022-04-20
- Last Posted Date
- 2022-04-20
- Lead Sponsor
- Sheikh Zayed Medical College
- Target Recruit Count
- 185
- Registration Number
- NCT05337085
Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia
- Conditions
- Interventions
- First Posted Date
- 2022-04-14
- Last Posted Date
- 2022-04-14
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 64
- Registration Number
- NCT05327088
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
Drug Development Updates
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