Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-

Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates

Phase 2
Completed
Conditions
Interventions
First Posted Date
2022-04-13
Last Posted Date
2022-04-13
Lead Sponsor
Mansoura University
Target Recruit Count
40
Registration Number
NCT05324891

Effect of Propofol on Postoperative Sleep Quality in Elderly Patients With Sleep Disorders

First Posted Date
2022-04-13
Last Posted Date
2022-10-03
Lead Sponsor
Xiangya Hospital of Central South University
Target Recruit Count
321
Registration Number
NCT05325762
Locations
🇨🇳

Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

🇨🇳

West China Hospital, Sichuan University, Chengdu, Sichuan, China

and more 1 locations

Dexmedetomine vs Dexamethasone in TAB Block for Abdominal Surgries

Phase 4
Conditions
Interventions
First Posted Date
2022-04-12
Last Posted Date
2022-04-12
Lead Sponsor
Ain Shams University
Target Recruit Count
45
Registration Number
NCT05323565
Locations
🇪🇬

Ain Shams University, Faculty of medicine, Cairo, Egypt

Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial

First Posted Date
2022-04-11
Last Posted Date
2024-04-22
Lead Sponsor
University of California, Irvine
Target Recruit Count
41
Registration Number
NCT05321121
Locations
🇺🇸

University of California, Irvine, Orange, California, United States

Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.

First Posted Date
2022-04-05
Last Posted Date
2022-04-05
Lead Sponsor
Sheikh Zayed Medical College
Target Recruit Count
71
Registration Number
NCT05311722

Sedation With Remimazolam During Spinal Anesthesia

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2022-03-31
Last Posted Date
2023-05-12
Lead Sponsor
Gangnam Severance Hospital
Target Recruit Count
62
Registration Number
NCT05305248
Locations
🇰🇷

Gangnam Severance Hospital, Seoul, Korea, Republic of

Using Dexmedetomidine Prior to Intubation in Neonates

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2022-03-31
Last Posted Date
2023-10-24
Lead Sponsor
Maimonides Medical Center
Target Recruit Count
30
Registration Number
NCT05304598
Locations
🇺🇸

Maimonides Medical Center, Brooklyn, New York, United States

Decatecholaminisation of Septic Shock With Dexmedetomidine and In-hospital Mortality

Phase 2
Completed
Conditions
Interventions
First Posted Date
2022-03-16
Last Posted Date
2023-05-06
Lead Sponsor
Mansoura University
Target Recruit Count
90
Registration Number
NCT05283083
Locations
🇪🇬

Mansoura University Hospitals, Mansoura, Aldakahlia, Egypt

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

First Posted Date
2022-03-15
Last Posted Date
2024-01-24
Lead Sponsor
Beth Israel Deaconess Medical Center
Target Recruit Count
70
Registration Number
NCT05279898
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2022-03-15
Last Posted Date
2023-10-31
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT05280223
Locations
🇪🇬

Emad Zarief Kamel Said, Assiut, Egypt

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