Metoclopramide
- Generic Name
- Metoclopramide
- Brand Names
- Gimoti, Reglan
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22ClN3O2
- CAS Number
- 364-62-5
- Unique Ingredient Identifier
- L4YEB44I46
- Background
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...
- Indication
Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...
- Associated Conditions
- Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
- Associated Therapies
- Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
- Conditions
- Interventions
- First Posted Date
- 2021-11-01
- Last Posted Date
- 2024-03-07
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 22
- Registration Number
- NCT05102591
- Locations
- 🇨🇦
Alberta Children's Hospital, Calgary, Alberta, Canada
Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy
- First Posted Date
- 2021-10-28
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Women and Infants Hospital of Rhode Island
- Target Recruit Count
- 30
- Registration Number
- NCT05098067
- Locations
- 🇺🇸
Women and Infants Hospital, Providence, Rhode Island, United States
Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery
- First Posted Date
- 2021-10-21
- Last Posted Date
- 2021-10-29
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Target Recruit Count
- 130
- Registration Number
- NCT05087615
- Locations
- 🇮🇷
Loghman Hakim Hospital, Tehran, Iran, Islamic Republic of
Metoclopramide for Acute Upper GI Bleeding
- Conditions
- Interventions
- First Posted Date
- 2021-02-25
- Last Posted Date
- 2023-10-02
- Lead Sponsor
- King Chulalongkorn Memorial Hospital
- Target Recruit Count
- 68
- Registration Number
- NCT04771481
- Locations
- 🇹🇭
Division of Gastroenterology, Faculty of Medicine, Chulalongkorn University, Bangkok, Pathumwan, Thailand
🇹🇭King chulalongkorn memorial hospital, Bangkok, Pathum Wan, Thailand
PROUD Study - Preventing Opioid Use Disorders
- Conditions
- Interventions
- Behavioral: Guided mindfulness exercisesOther: Self-administered aromatherapyDrug: Baby aspirinDrug: Tylenol/AcetaminophenDrug: PregabalinDrug: PrednisoneDrug: MeloxicamDrug: PrilosecDrug: TramadolDrug: VoltarenDrug: ZofranDrug: PepcidDrug: ReglanDrug: VersedDrug: LidocaineDrug: PropofolDrug: AncefDrug: Tranexamic Acid (TXA)Drug: DecadronDrug: Bupivacaine hydrochlorideDrug: Toradol
- First Posted Date
- 2021-02-23
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Emory University
- Target Recruit Count
- 57
- Registration Number
- NCT04766996
- Locations
- 🇺🇸
Emory University Orthopaedic and Spine Hospital, Atlanta, Georgia, United States
Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room
- Conditions
- Interventions
- First Posted Date
- 2021-01-27
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 323
- Registration Number
- NCT04726592
- Locations
- 🇫🇷
Hôpital Lariboisière, Paris, Ile-de-France, France
Intravenous Metoclopramide Versus Dexketoprofen Trometamol Versus Metoclopramide+ Dexketoprofen Trometamol in Migraine
- Conditions
- Interventions
- First Posted Date
- 2020-02-05
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- Adiyaman University Research Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT04252521
- Locations
- 🇹🇷
Adiyaman University Research Hospital, Adıyaman, Central, Turkey
Palliative Management of Inoperable Malignant Bowel Obstruction
- Conditions
- Interventions
- First Posted Date
- 2019-07-22
- Last Posted Date
- 2022-11-29
- Lead Sponsor
- Roswell Park Cancer Institute
- Target Recruit Count
- 15
- Registration Number
- NCT04027348
- Locations
- 🇺🇸
Roswell Park Cancer Institute, Buffalo, New York, United States
Restoration of Hypoglycemia Awareness With Metoclopramide
- First Posted Date
- 2019-05-31
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Simon Fisher
- Target Recruit Count
- 36
- Registration Number
- NCT03970720
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
🇺🇸University of Kentucky, Lexington, Kentucky, United States
Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CS
- First Posted Date
- 2019-04-30
- Last Posted Date
- 2019-10-07
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 60
- Registration Number
- NCT03932578
- Locations
- 🇪🇬
Mansoura University Hospital, Mansoura, Dakahlia, Egypt
Drug Development Updates
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