Metoclopramide
- Generic Name
- Metoclopramide
- Brand Names
- Gimoti, Reglan
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22ClN3O2
- CAS Number
- 364-62-5
- Unique Ingredient Identifier
- L4YEB44I46
- Background
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...
- Indication
Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...
- Associated Conditions
- Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
- Associated Therapies
- Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients
- Conditions
- Interventions
- First Posted Date
- 2018-06-18
- Last Posted Date
- 2020-07-09
- Lead Sponsor
- Barzilai Medical Center
- Target Recruit Count
- 60
- Registration Number
- NCT03560583
TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2019-09-24
- Lead Sponsor
- Millennium Pharmaceuticals, Inc.
- Target Recruit Count
- 1
- Registration Number
- NCT03477903
- Locations
- 🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada
🇬🇧Cardiff and Vale University Health Board, Cardiff, Wales, United Kingdom
🇨🇦Royal Columbian Hospital, New Westminster, British Columbia, Canada
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
- Conditions
- Interventions
- First Posted Date
- 2018-02-15
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 83
- Registration Number
- NCT03435003
- Locations
- 🇺🇸
Stony Brook University Hospital, Stony Brook, New York, United States
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
- Conditions
- Interventions
- First Posted Date
- 2017-12-26
- Last Posted Date
- 2017-12-26
- Lead Sponsor
- University of Malaya
- Target Recruit Count
- 191
- Registration Number
- NCT03383315
- Locations
- 🇲🇾
Sarawak General Hospital, Kuching, Sarawak, Malaysia
Greater Occipital Nerve Block Versus Metoclopramide
- Conditions
- Interventions
- First Posted Date
- 2017-08-31
- Last Posted Date
- 2021-09-22
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 99
- Registration Number
- NCT03269435
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Metoclopramide for Post Traumatic Headache
- Conditions
- Interventions
- First Posted Date
- 2017-07-18
- Last Posted Date
- 2021-11-09
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 160
- Registration Number
- NCT03220958
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
- Conditions
- Interventions
- First Posted Date
- 2017-03-16
- Last Posted Date
- 2018-01-18
- Lead Sponsor
- Brooke Army Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT03081416
- Locations
- 🇺🇸
Brooke Army Medical Center, San Antonio, Texas, United States
Metoclopramide for Post-Traumatic Headache. A Pilot Study
- Conditions
- Interventions
- First Posted Date
- 2017-02-17
- Last Posted Date
- 2018-07-31
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 21
- Registration Number
- NCT03056352
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Treatment Algorithm for Nausea and Vomiting in the Palliative Phase
- Conditions
- Interventions
- First Posted Date
- 2017-01-11
- Last Posted Date
- 2017-01-11
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT03017391
Study to Evaluate the Effect of Aprepitant in Children and Adolescents Receiving AML Remission Induction Chemotherapy
- Conditions
- Interventions
- First Posted Date
- 2016-12-01
- Last Posted Date
- 2017-01-25
- Lead Sponsor
- Dr Atul Sharma
- Target Recruit Count
- 116
- Registration Number
- NCT02979548
- Locations
- 🇮🇳
Irch, Aiims , New Delhi , India, New Delhi, DEL, India
Drug Development Updates
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