Metronidazole

Generic Name: Metronidazole

Brand Names: Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole

Drug Type: Small Molecule

Chemical Formula: C_₆H_₉N_₃O_₃

CAS Number: 443-48-1

Unique Ingredient Identifier: 140QMO216E

Background: Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication: Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions: Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis

Associated Therapies: -

Clinical Trials

Is it Effective to Treat Patients With Blastocystis Hominis Infection?

Phase 4

Conditions: Blastocystis Hominis Infections

Interventions: Drug: Placebo
Drug: Metronidazole

First Posted Date: 2012-01-30

Last Posted Date: 2022-08-23

Lead Sponsor: University of Lausanne Hospitals

Target Recruit Count: 200

Registration Number: NCT01521403

Locations: 🇨🇭
Travel Clinic, Department of Ambulatory Care and Community Medicine, University Hospital of Lausanne, Switzerland, Lausanne, Vaud, Switzerland

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Phase 3

Completed

Conditions: Complicated Intra-Abdominal Infection

Interventions: Drug: Meropenem
Drug: CAZ-AVI
Drug: Metronidazole

First Posted Date: 2011-12-26

Last Posted Date: 2017-09-06

Lead Sponsor: Pfizer

Target Recruit Count: 493

Registration Number: NCT01499290

Locations: 🇺🇦
Research Site, Zaporizhzhya, Ukraine

A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection

Phase 3

Completed

Conditions: Intra-abdominal Infections

Interventions: Drug: Metronidazole
Drug: Ceftriaxone sodium

First Posted Date: 2011-11-17

Last Posted Date: 2014-01-24

Lead Sponsor: Pfizer

Target Recruit Count: 38

Registration Number: NCT01473836

Locations: 🇯🇵
Iida Municipal Hospital, Iida, Nagano, Japan
🇯🇵
National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka, Japan
🇯🇵
Koshigaya Municipal Hospital, Koshigaya, Saitama, Japan

and more 12 locations

Prospective Study of Clostridium Difficile in Children Undergoing Colonoscopy

Not Applicable

Withdrawn

Conditions: C. Difficile Infection

Interventions: Drug: metronidazole

First Posted Date: 2011-11-17

Last Posted Date: 2019-07-25

Lead Sponsor: State University of New York at Buffalo

Registration Number: NCT01472978

Locations: 🇺🇸
Women and Children's Hospital, Buffalo, New York, United States

Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo

Phase 4

Completed

Conditions: Rosacea

Interventions: Drug: Placebo
Drug: Doxycycline
Drug: Metronidazole

First Posted Date: 2011-08-31

Last Posted Date: 2022-08-01

Lead Sponsor: Galderma R&D

Target Recruit Count: 235

Registration Number: NCT01426269

Locations: 🇺🇸
ATS Clinical Research, Santa Monica, California, United States
🇺🇸
Melissa L. F. Knuckles M.D., P.S.C., Richmond, Kentucky, United States
🇺🇸
Dadeland Dermatology, Coral Gables, Florida, United States

and more 7 locations