Isosorbide dinitrate
- Generic Name
- Isosorbide dinitrate
- Brand Names
- Bidil, Dilatrate, Isordil
- Drug Type
- Small Molecule
- Chemical Formula
- C6H8N2O8
- CAS Number
- 87-33-2
- Unique Ingredient Identifier
- IA7306519N
- Background
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
- Indication
For the prevention of angina pectoris due to coronary artery disease.
- Associated Conditions
- Angina Pectoris, Heart Failure
- Associated Therapies
- -
Intensive Arterial Pressure Control in Acute Coronary Syndrome
- First Posted Date
- 2014-05-09
- Last Posted Date
- 2022-08-24
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 1500
- Registration Number
- NCT02135315
- Locations
- 🇹🇳
university of Monastir, Monastir, Tunisia
Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2013-04-02
- Last Posted Date
- 2015-08-14
- Lead Sponsor
- University of Cape Town
- Target Recruit Count
- 500
- Registration Number
- NCT01822808
- Locations
- 🇿🇦
Hatter Institute for Cardiovascular Research in Africa, Cape Town, Western Cape, South Africa
Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction
- Conditions
- Interventions
- First Posted Date
- 2012-01-24
- Last Posted Date
- 2022-06-21
- Lead Sponsor
- Corporal Michael J. Crescenz VA Medical Center
- Target Recruit Count
- 44
- Registration Number
- NCT01516346
- Locations
- 🇺🇸
Philadelphia VA Medical Center, Philadelphia, Pennsylvania, United States
A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis
- First Posted Date
- 2012-01-20
- Last Posted Date
- 2014-08-05
- Target Recruit Count
- 120
- Registration Number
- NCT01513070
- Locations
- 🇨🇳
Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing, Beijing, China
To Compare the Pharmacokinetics Profiles of ISO 20, IBU 200 and IBU Plus ISO Combinations 200 + 20
- Conditions
- Interventions
- First Posted Date
- 2011-11-23
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- Parent Project, Italy
- Target Recruit Count
- 12
- Registration Number
- NCT01478022
- Locations
- 🇮🇹
Clinical Phase 1 Unit - Luigi Sacco Hospital, Milan, Italy
Treatment of Orthostatic Intolerance
- Conditions
- Interventions
- Drug: AtomoxetineDrug: AcetazolamideDietary Supplement: MelatoninOther: NO DrugDrug: Isosorbide DinitrateRadiation: PlaceboDevice: Breathing DeviceOther: Drinking WaterProcedure: IV SalineDevice: Abdominal binderDrug: IndomethacinDrug: MidodrineDrug: MecamylamineDrug: ClonidineDrug: EntacaponeDrug: memantineDrug: ModafinilDrug: OctreotideDrug: SertralineDrug: Atomoxetine & PropranololDrug: Entacapone & PropranololDrug: PropranololDrug: Modafinil & Propranolol
- First Posted Date
- 2005-12-06
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Satish R. Raj
- Target Recruit Count
- 150
- Registration Number
- NCT00262470
- Locations
- 🇺🇸
Vanderbilt University Autonomic Dysfunction Center, Nashville, Tennessee, United States
Asymptomatic Cardiac Ischemia Pilot (ACIP) Study
- Conditions
Drug Development Updates
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