Clomifene
- Generic Name
- Clomifene
- Brand Names
- Clomid
- Drug Type
- Small Molecule
- Chemical Formula
- C26H28ClNO
- CAS Number
- 911-45-5
- Unique Ingredient Identifier
- 1HRS458QU2
- Background
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
- Indication
Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
- Associated Conditions
- Ovulatory Dysfunction
Hypogonadism in Young Men With Type 2 Diabetes
- Conditions
- Hypogonadotropic HypogonadismType 2 Diabetes
- Interventions
- First Posted Date
- 2010-07-01
- Last Posted Date
- 2019-10-04
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 5
- Registration Number
- NCT01155518
- Locations
- 🇺🇸
Millard Fillmore Gates Hospital, Buffalo, New York, United States
Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
- Conditions
- PregnancyUnexplained Infertility
- Interventions
- Drug: Follicle Stimulating Hormone (gonadotropin)
- First Posted Date
- 2010-01-08
- Last Posted Date
- 2015-02-02
- Lead Sponsor
- Yale University
- Target Recruit Count
- 900
- Registration Number
- NCT01044862
- Locations
- 🇺🇸
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
🇺🇸University of Colorado, Aurora, Colorado, United States
🇺🇸University of Alabama Birmingham, Birmingham, Alabama, United States
Traditional Clomiphene Citrate Administration vs. Stair-step Approach
- Conditions
- Ovulatory DysfunctionAnovulationOvulation Induction
- Interventions
- First Posted Date
- 2009-11-05
- Last Posted Date
- 2018-01-08
- Lead Sponsor
- University of Oklahoma
- Target Recruit Count
- 120
- Registration Number
- NCT01008319
- Locations
- 🇺🇸
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Short-term Structured Exercise Training Program Plus Diet Intervention in Patients With Polycystic Ovary Syndrome (PCOS)
- Conditions
- Polycystic Ovary SyndromeAnovulation
- Interventions
- Other: SET-diet plus clomipheneBehavioral: Structured exercise program plus hypocaloric diet
- First Posted Date
- 2009-10-29
- Last Posted Date
- 2010-11-03
- Lead Sponsor
- University Magna Graecia
- Target Recruit Count
- 96
- Registration Number
- NCT01004068
- Locations
- 🇮🇹
"Pugliese" Hospital, Catanzaro, Italy
Comparison of Micro-dose Human Chorionic Gonadotropin (hCG) With Human Menopausal Gonadotropin (HMG) in Polycystic Ovary Syndrome
- Conditions
- Endocrine System DiseasesGonadal Disorders
- Interventions
- Drug: low dose human chorionic gonadotropin
- First Posted Date
- 2009-07-28
- Last Posted Date
- 2011-07-15
- Lead Sponsor
- Royan Institute
- Target Recruit Count
- 10
- Registration Number
- NCT00947713
- Locations
- 🇮🇷
Royan institute, Reproductive Medicine Research Centre, ACECR, Tehran, Iran, Islamic Republic of
Comparison of Clomiphene Citrate and Gonadotropins in Ovulation Induction Cycles
- First Posted Date
- 2009-02-04
- Last Posted Date
- 2012-03-28
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 40
- Registration Number
- NCT00835744
- Locations
- 🇧🇪
UZ Brussel, Jette, Belgium
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist
- Conditions
- Ovarian Stimulation
- Interventions
- Procedure: UltrasoundDrug: rFSHDrug: gonadotopin (HMG)
- First Posted Date
- 2009-01-28
- Last Posted Date
- 2009-01-28
- Lead Sponsor
- Yazd Research & Clinical Center for Infertility
- Target Recruit Count
- 200
- Registration Number
- NCT00830492
- Locations
- 🇮🇷
Yazd Research and Clinical Center For Infertility, Yazd, Iran, Islamic Republic of
Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females
- Conditions
- Infertility
- Interventions
- First Posted Date
- 2008-11-24
- Last Posted Date
- 2015-09-09
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 350
- Registration Number
- NCT00796289
- Locations
- 🇺🇸
Florida Fertility Institute, Clearwater, Florida, United States
🇺🇸All Women's Healthcare of Wesy Broward, Inc., Plantation, Florida, United States
🇺🇸A Woman's Center for Reproductive Medicine, Baton Rouge, Louisiana, United States
PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene
- Conditions
- Polycystic Ovary Syndrome
- Interventions
- First Posted Date
- 2008-11-21
- Last Posted Date
- 2008-11-21
- Lead Sponsor
- University of Auckland, New Zealand
- Target Recruit Count
- 171
- Registration Number
- NCT00795808
- Locations
- 🇳🇿
University of Auckland, Auckland, New Zealand
Pregnancy in Polycystic Ovary Syndrome II
- Conditions
- Polycystic Ovary SyndromePregnancy
- Interventions
- First Posted Date
- 2008-07-21
- Last Posted Date
- 2018-06-14
- Lead Sponsor
- Yale University
- Target Recruit Count
- 750
- Registration Number
- NCT00719186
- Locations
- 🇺🇸
Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States
🇺🇸University of Colorado, Aurora, Colorado, United States
🇺🇸Yale University, New Haven, Connecticut, United States
Drug Development Updates
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