Clomifene
- Generic Name
- Clomifene
- Brand Names
- Clomid
- Drug Type
- Small Molecule
- Chemical Formula
- C26H28ClNO
- CAS Number
- 911-45-5
- Unique Ingredient Identifier
- 1HRS458QU2
- Background
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
- Indication
Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
- Associated Conditions
- Ovulatory Dysfunction
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Not Applicable
Completed
- Conditions
- Polycystic Ovary Syndrome
- Interventions
- First Posted Date
- 2013-07-30
- Last Posted Date
- 2013-07-30
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 110
- Registration Number
- NCT01910766
- Locations
- 🇪🇬
Mansoura University Hospitals, Mansoura, Dakahlia, Egypt
Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS
Early Phase 1
Completed
- Conditions
- Polycystic Ovary SyndromeInfertility
- Interventions
- Drug: induction of ovulation using letrozole-pioglitazone-metforminRadiation: transvaginal ultrasoundOther: body mass index (BMI) calculationOther: pretreatment blood urea and serum creatinineOther: serum estradiol (E2) on day 12Other: serum progesterone on day 21Other: blood urea and serum creatinine every month
- First Posted Date
- 2013-07-26
- Last Posted Date
- 2015-10-20
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT01909141
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Clomid in Men With Low Testosterone With and Without Prior Treatment
- First Posted Date
- 2013-07-22
- Last Posted Date
- 2021-03-10
- Lead Sponsor
- Phoenix VA Health Care System
- Target Recruit Count
- 42
- Registration Number
- NCT01904734
- Locations
- 🇺🇸
Phoenix VA Health Care System, Phoenix, Arizona, United States
Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
Phase 2
Completed
- Conditions
- HypogonadismOpioid-Related DisordersMale Infertility
- Interventions
- Drug: Placebo
- First Posted Date
- 2013-06-18
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 13
- Registration Number
- NCT01880086
- Locations
- 🇺🇸
Weill Cornell Medical College, Department of Urology, New York, New York, United States
Clomiphene Citrate Plus uFSH Versus Aromatase Inhibitor Plus uFSH in Clomiphene Resistant Infertile PCOS Women
Not Applicable
- Conditions
- Polycystic Ovary SyndromeInfertility
- Interventions
- Drug: Aromatase inhibitor (litrezole) plus uFSH arm
- First Posted Date
- 2013-02-15
- Last Posted Date
- 2013-03-06
- Lead Sponsor
- Mansoura Integrated Fertility Center
- Target Recruit Count
- 160
- Registration Number
- NCT01793038
- Locations
- 🇪🇬
Mansoura Integrated fertility center, Mansoura, Dekahlia, Egypt
Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles
- First Posted Date
- 2013-02-15
- Last Posted Date
- 2013-02-15
- Lead Sponsor
- Fundació Privada Eugin
- Target Recruit Count
- 10
- Registration Number
- NCT01791751
- Locations
- 🇪🇸
Clínica EUGIN, Barcelona, Spain
Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)
Not Applicable
Terminated
- Conditions
- Polycystic Ovary SyndromeInfertility
- Interventions
- First Posted Date
- 2012-10-31
- Last Posted Date
- 2020-09-29
- Lead Sponsor
- University of Illinois at Chicago
- Target Recruit Count
- 27
- Registration Number
- NCT01718444
- Locations
- 🇺🇸
University of Illinois at Chicago, Chicago, Illinois, United States
Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome
Not Applicable
Completed
- Conditions
- Polycystic Ovary Syndrome
- Interventions
- First Posted Date
- 2012-09-06
- Last Posted Date
- 2012-09-07
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 200
- Registration Number
- NCT01679574
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin
Phase 3
Withdrawn
- Conditions
- Polycystic Ovary SyndromeInsulin Resistance
- Interventions
- First Posted Date
- 2012-07-12
- Last Posted Date
- 2015-07-28
- Lead Sponsor
- Clinique Ovo
- Registration Number
- NCT01638988
- Locations
- 🇨🇦
Clinique Ovo, Montréal, Quebec, Canada
Efficacy Study of Raloxifene to Induce Ovulation in Polycystic Ovarian Syndrome
Not Applicable
Terminated
- Conditions
- Polycystic Ovarian Syndrome
- Interventions
- First Posted Date
- 2012-05-30
- Last Posted Date
- 2018-09-20
- Lead Sponsor
- Bruce Lessey
- Target Recruit Count
- 3
- Registration Number
- NCT01607320
- Locations
- 🇺🇸
Greenville Hospital System, Greenville, South Carolina, United States
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