Clomifene

Generic Name
Clomifene
Brand Names
Clomid
Drug Type
Small Molecule
Chemical Formula
C26H28ClNO
CAS Number
911-45-5
Unique Ingredient Identifier
1HRS458QU2
Background

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.

Indication

Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.

Associated Conditions
Ovulatory Dysfunction
Associated Therapies
-

Efficacy Study of Raloxifene to Induce Ovulation in Polycystic Ovarian Syndrome

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2012-05-30
Last Posted Date
2018-09-20
Lead Sponsor
Bruce Lessey
Target Recruit Count
3
Registration Number
NCT01607320
Locations
🇺🇸

Greenville Hospital System, Greenville, South Carolina, United States

Clomifene Citrate as First Line Treatment in in Vitro Fertilization Cycles for Patients With Lower Ovarian Reserve

First Posted Date
2011-07-08
Last Posted Date
2011-07-12
Lead Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Target Recruit Count
289
Registration Number
NCT01389713
Locations
🇮🇹

Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) Response to Low Dose Clomiphene Citrate in Normally Menstruating Fertile Women

Phase 1
Completed
Conditions
First Posted Date
2011-04-22
Last Posted Date
2012-12-20
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
25
Registration Number
NCT01340521
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Differential Effects of Clomiphene Citrate in Women Undergoing Superovulation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-02-07
Last Posted Date
2016-06-28
Lead Sponsor
University of Utah
Target Recruit Count
20
Registration Number
NCT01291056
Locations
🇺🇸

University of Utah, Salt Lake City, Utah, United States

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

First Posted Date
2011-02-04
Last Posted Date
2015-02-24
Lead Sponsor
Robert Bosch Gesellschaft für Medizinische Forschung mbH
Target Recruit Count
20
Registration Number
NCT01289756
Locations
🇩🇪

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology and University of Tuebingen, Stuttgart, BW, Germany

Mild Stimulation Protocol Versus Microdose Gonadotropin-releasing Hormone Agonist Flare up Protocol in Poor Responders

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-10-01
Last Posted Date
2010-10-01
Lead Sponsor
Yazd Medical University
Target Recruit Count
159
Registration Number
NCT01213147
Locations
🇮🇷

Yazd Research and Clinical Center for Infertility, Yazd, Iran, Islamic Republic of

Minimal Stimulation or Clomiphene Citrate in Treatment of Polycystic Ovary Syndrome

First Posted Date
2010-07-07
Last Posted Date
2010-07-19
Lead Sponsor
Mansoura University
Target Recruit Count
113
Registration Number
NCT01157312
Locations
🇪🇬

Mansoura University Hospitals,OB/GYN department, Mansoura, Dakahlia Governorate, Egypt

Hypogonadism in Young Men With Type 2 Diabetes

First Posted Date
2010-07-01
Last Posted Date
2019-10-04
Lead Sponsor
State University of New York at Buffalo
Target Recruit Count
5
Registration Number
NCT01155518
Locations
🇺🇸

Millard Fillmore Gates Hospital, Buffalo, New York, United States

Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation

First Posted Date
2010-01-08
Last Posted Date
2015-02-02
Lead Sponsor
Yale University
Target Recruit Count
900
Registration Number
NCT01044862
Locations
🇺🇸

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

🇺🇸

University of Colorado, Aurora, Colorado, United States

🇺🇸

University of Alabama Birmingham, Birmingham, Alabama, United States

and more 11 locations

Traditional Clomiphene Citrate Administration vs. Stair-step Approach

First Posted Date
2009-11-05
Last Posted Date
2018-01-08
Lead Sponsor
University of Oklahoma
Target Recruit Count
120
Registration Number
NCT01008319
Locations
🇺🇸

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

© Copyright 2024. All Rights Reserved by MedPath