MedPath

Clomifene

Generic Name
Clomifene
Brand Names
Clomid
Drug Type
Small Molecule
Chemical Formula
C26H28ClNO
CAS Number
911-45-5
Unique Ingredient Identifier
1HRS458QU2
Background

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.

Indication

Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.

Associated Conditions
Ovulatory Dysfunction

Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Phase 3
Completed
Conditions
Infertility
Interventions
First Posted Date
2017-08-07
Last Posted Date
2017-08-07
Lead Sponsor
Assiut University
Target Recruit Count
100
Registration Number
NCT03241472

Clomiphene Citrate Stair-Step Protocol

Not Applicable
Conditions
Polycystic Ovary
Interventions
First Posted Date
2017-06-07
Last Posted Date
2018-06-28
Lead Sponsor
Ain Shams Maternity Hospital
Target Recruit Count
60
Registration Number
NCT03178500
Locations
🇪🇬

Ain Shams University Maternity Hospital, Cairo, Egypt

Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome

Phase 3
Recruiting
Conditions
Polycystic Ovary Syndrome
Reproductive Medicine
Interventions
Dietary Supplement: Myo-Inositol + Levomefolic acid
Dietary Supplement: placebo
First Posted Date
2017-02-23
Last Posted Date
2024-04-19
Lead Sponsor
University Hospital, Lille
Target Recruit Count
276
Registration Number
NCT03059173
Locations
🇫🇷

CHU de Lille hôpital Jeanne de Flandre, Lille, France

Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting

Phase 1
Completed
Conditions
Sports Drug Abuse
Abuse of Steroids or Hormones
Interventions
First Posted Date
2017-01-23
Last Posted Date
2020-01-30
Lead Sponsor
Stuart Willick
Target Recruit Count
12
Registration Number
NCT03028532
Locations
🇺🇸

Heidi Jo Hansen, Salt Lake City, Utah, United States

Sildenafil Effect After Ovulation Induction

Phase 4
Conditions
Infertility
Interventions
First Posted Date
2016-09-07
Last Posted Date
2019-09-23
Lead Sponsor
Cairo University
Target Recruit Count
100
Registration Number
NCT02890238
Locations
🇪🇬

Kasr Alainy medical school, Cairo, Egypt

Protocol to Minimize Injections and Blood Draws for Women Undergoing in Vitro Fertilization

Not Applicable
Completed
Conditions
Infertility
Interventions
First Posted Date
2016-08-12
Last Posted Date
2019-03-19
Lead Sponsor
New Hope Fertility Center
Target Recruit Count
4
Registration Number
NCT02865681
Locations
🇺🇸

New Hope Fertility Center, New York, New York, United States

Combined Letrozole and Clomid in Women With Infertility and PCOS

Phase 4
Completed
Conditions
Polycystic Ovary Syndrome
Infertility
Interventions
First Posted Date
2016-06-16
Last Posted Date
2019-09-27
Lead Sponsor
Rachel Mejia
Target Recruit Count
70
Registration Number
NCT02802865
Locations
🇺🇸

University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States

Letrozole and Sequential Clomiphene to Improve the Outcome of Embryo Transfer

Not Applicable
Conditions
Female Infertility Due to Nonimplantation of Ovum
Interventions
First Posted Date
2016-05-18
Last Posted Date
2017-06-23
Lead Sponsor
Navy General Hospital, Beijing
Target Recruit Count
100
Registration Number
NCT02775877
Locations
🇨🇳

Department of Obstetrics and Gynecology, Navy General Hospital., Beijing, Beijing, China

NAC in CC Resistant PCOS After LOD

Phase 2
Completed
Conditions
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Interventions
Drug: N-acetyl-cysteine
First Posted Date
2016-05-18
Last Posted Date
2017-05-02
Lead Sponsor
Ain Shams University
Target Recruit Count
144
Registration Number
NCT02775734
Locations
🇪🇬

Ain Shams University Maternity Hospital, Cairo, Egypt

Sildenafil Vaginal Gel Co-treatment With Clomiphene Citrate in Infertile Women With Thin Endometrium

Not Applicable
Completed
Conditions
Anovulation
Interventions
First Posted Date
2016-03-17
Last Posted Date
2020-05-05
Lead Sponsor
Assiut University
Target Recruit Count
42
Registration Number
NCT02710981
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