DeepMed Research

Clomifene

Generic Name: Clomifene

Brand Names: Clomid

Drug Type: Small Molecule

Chemical Formula: C_₂₆H_₂₈ClNO

CAS Number: 911-45-5

Unique Ingredient Identifier: 1HRS458QU2

Background: A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.

Indication: Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.

Associated Conditions: Ovulatory Dysfunction

Clinical Trials

Predictors of Ovarian Response During Clomiphene Citrate Ovulation Induction in Patients With Polycystic Ovary Syndrome

Not Applicable

Completed

Conditions: Anovulation

Interventions: Drug: clomiphen citrate

First Posted Date: 2014-10-21

Last Posted Date: 2014-10-21

Lead Sponsor: Menoufia Obstetrics and Gynecology Group

Target Recruit Count: 150

Registration Number: NCT02269306

Locations: 🇪🇬
Menoufia University hospital, Shebin Elkom, Menoufia, Egypt

Human Chorionic Gonadotrophin & Trigger

Phase 3

Conditions: Ovulation Disorder

Interventions: Drug: clomiphene citrate alone
Drug: Human chorionic gonadotrophin

First Posted Date: 2014-10-15

Last Posted Date: 2017-02-08

Lead Sponsor: Cairo University

Target Recruit Count: 200

Registration Number: NCT02264847

Locations: 🇪🇬
faculty of medicine , Cairo University, Cairo, Egypt

Endobarrier Treatment in Women With PCOS

Phase 3

Conditions: Polycystic Ovary Syndrome

Interventions: Device: Endobarrier treatment in PCOS
Drug: clomiphene citrate treatment

First Posted Date: 2014-10-02

Last Posted Date: 2014-10-02

Lead Sponsor: Sheba Medical Center

Target Recruit Count: 50

Registration Number: NCT02255578

Locations: 🇮🇱
Sheba Medical Center, Ramat Gan, Israel

Clomiphene Citrate in Combination With Gonadotropins for Ovarian Stimulation in Women With Poor Ovarian Response.

Phase 2

Conditions: Female Infertility

Interventions: Drug: Clomiphene citrate
Drug: Gonadotropins

First Posted Date: 2014-09-11

Last Posted Date: 2014-09-11

Lead Sponsor: University of Athens

Target Recruit Count: 50

Registration Number: NCT02237755

Clomiphene Citrate Plus Gonadotropins and GnRH Antagonist Versus Flexible GnRH Antagonist Protocol Versus Microdose GnRH Agonist Protocol in Poor Responders Undergoing IVF

Phase 4

Conditions: IVF
GnRH Agonist
GnRH Antagonist
Poor Responders
Clomiphene Citrate

Interventions: Drug: Triptorelin plus daily FSH anh LH
Drug: Clomiphene citrate
Drug: Daily FSH and LH plus Cetrorelix

First Posted Date: 2014-07-28

Last Posted Date: 2014-07-28

Lead Sponsor: Bioroma

Target Recruit Count: 250

Registration Number: NCT02201914

Locations: 🇮🇹
Bioroma, Rome, Italy

Concomitant CC and E2 Versus CC Alone in Ovulation Induction

Phase 4

Conditions: Infertility
Anovulation

Interventions: Drug: Clomiphene citrate and Placebo
Drug: Clomiphene citrate and Estradiol

First Posted Date: 2014-07-10

Last Posted Date: 2017-03-22

Lead Sponsor: Maher elesawi kamel elesawi

Target Recruit Count: 600

Registration Number: NCT02186782

Locations: 🇪🇬
Obstetrics and Gynecology Department in Mansoura University Hospital, Mansoura, Dakahlia, Egypt
🇪🇬
Private practice settings, Mit Ghamr, Dakahlia, Egypt

Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism

Not Applicable

Withdrawn

Conditions: Non Obstructive Azoospermia
Hypogonadism

Interventions: Drug: Placebo
Drug: Clomiphene

First Posted Date: 2014-05-13

Last Posted Date: 2020-10-05

Lead Sponsor: University of Illinois at Chicago

Registration Number: NCT02137265

Locations: 🇪🇸
University of Valencia, Valencia, Province Of Valencia, Spain

Luteal Phase Versus Follicular Phase Administration of Clomiphene Citrate in PCOS, A Randomized Controlled Trial

Phase 1

Conditions: PCOS

Interventions: Drug: Clomiphene Citrate

First Posted Date: 2013-12-31

Last Posted Date: 2014-03-11

Lead Sponsor: Ain Shams Maternity Hospital

Target Recruit Count: 90

Registration Number: NCT02024984

Locations: 🇪🇬
Ain Shams Maternity Hospital, Cairo, Egypt

Clomiphene Stair-Step Protocol for Ovulation Induction in Women With Polycystic Ovarian Syndrome

Not Applicable

Completed

Conditions: Polycystic Ovary Syndrome

Interventions: Drug: clomiphene

First Posted Date: 2013-10-01

Last Posted Date: 2013-10-01

Lead Sponsor: Kufa University

Target Recruit Count: 140

Registration Number: NCT01953796

Locations: 🇮🇶
Basima Al- Ghazali, Najaf, Kufa, Iraq

Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: clomiphene plus gonadotropins
Drug: Leuprolide flare

First Posted Date: 2013-08-13

Last Posted Date: 2024-08-02

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 23

Registration Number: NCT01921166

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