Botulinum toxin type A
- Generic Name
- Botulinum toxin type A
- Brand Names
- Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-43-1
- Unique Ingredient Identifier
- 0A6JH35GMQ
- Background
In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...
- Indication
Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
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- Associated Conditions
- Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis
- Associated Therapies
- -
Efficacy and Functional Outcomes of Botulinum Toxin A Injections to Hamstrings in Flexed Knee Gait in Cerebral Palsy
- Conditions
- First Posted Date
- 2005-12-02
- Last Posted Date
- 2009-02-05
- Lead Sponsor
- Shriners Hospitals for Children
- Target Recruit Count
- 250
- Registration Number
- NCT00261131
Intra-articularInjection of Botulinum Toxin Type
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2005-09-21
- Lead Sponsor
- Minneapolis Veterans Affairs Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT00211679
- Locations
- 🇺🇸
Minneapolis VAMC, Minneapolis, Minnesota, United States
Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2016-06-01
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 20
- Registration Number
- NCT00178945
- Locations
- 🇺🇸
Vanderbilt Department of Neurology, Nashville, Tennessee, United States
A Study Evaluating Botulinum Toxin Type A in Subjects With Postherpetic Neuralgia
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2011-05-30
- Lead Sponsor
- Allergan
- Target Recruit Count
- 117
- Registration Number
- NCT00168441
A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2011-05-30
- Lead Sponsor
- Allergan
- Target Recruit Count
- 193
- Registration Number
- NCT00168402
Vanderbilt University Spasticity Management Program Evaluation Plan
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2007-08-20
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 20
- Registration Number
- NCT00179114
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Botulinum Toxin (BOTOX) for Cerebral Palsy
- Conditions
- First Posted Date
- 2003-05-19
- Last Posted Date
- 2016-09-26
- Target Recruit Count
- 40
- Registration Number
- NCT00060957
- Locations
- 🇺🇸
Children's Hospital and Regional Medical Center, Seattle, Washington, United States
Study of Botulinum Toxin in Patients With Primary Hyperhidrosis
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Registration Number
- NCT00004480
- Locations
- 🇺🇸
Mount Sinai School of Medicine, New York, New York, United States
Randomized Study of Botulinum Toxin Type A for Achalasia
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- University of Texas
- Target Recruit Count
- 56
- Registration Number
- NCT00004416
Drug Development Updates
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