Botulinum toxin type A
- Generic Name
- Botulinum toxin type A
- Brand Names
- Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-43-1
- Unique Ingredient Identifier
- 0A6JH35GMQ
- Background
In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...
- Indication
Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
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- Associated Conditions
- Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis
- Associated Therapies
- -
Botulinum Toxin to Treat Restless Legs Syndrome
- First Posted Date
- 2007-05-28
- Last Posted Date
- 2012-04-26
- Target Recruit Count
- 6
- Registration Number
- NCT00479154
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Intensive Strength Training in Children With Cerebral Palsy - Effect on Hand Function
- Conditions
- Interventions
- First Posted Date
- 2007-04-30
- Last Posted Date
- 2016-04-18
- Lead Sponsor
- St. Olavs Hospital
- Target Recruit Count
- 10
- Registration Number
- NCT00467207
- Locations
- 🇳🇴
St. Olavs Hospital, Trondheim, Norway
Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome
- Conditions
- Interventions
- First Posted Date
- 2007-04-23
- Last Posted Date
- 2014-02-03
- Lead Sponsor
- Daniel Stephan Engeler
- Target Recruit Count
- 11
- Registration Number
- NCT00464373
- Locations
- 🇨🇭
Department of Urology, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland
Comparative Study of the Effect of Dysport and Botox
- Conditions
- First Posted Date
- 2007-02-13
- Last Posted Date
- 2007-02-13
- Lead Sponsor
- Laserklinik Karlsruhe
- Target Recruit Count
- 24
- Registration Number
- NCT00434863
- Locations
- 🇩🇪
Laserklinik Karlsruhe, Karlsruhe, BW, Germany
A Study Of BOTOX For The Treatment Of Glabellar Lines
- Conditions
- Interventions
- First Posted Date
- 2006-12-07
- Last Posted Date
- 2017-05-31
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 256
- Registration Number
- NCT00408785
- Locations
- 🇨🇳
GSK Investigational Site, Shanghai, China
Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
- First Posted Date
- 2006-11-23
- Last Posted Date
- 2018-05-21
- Lead Sponsor
- Minneapolis Veterans Affairs Medical Center
- Target Recruit Count
- 54
- Registration Number
- NCT00403273
- Locations
- 🇺🇸
Minneapolis VA Medical Center, Minneapolis, Minnesota, United States
Pilot Study to Assess the Efficacy of Botulinum Toxin A Treatments on Pain and Disability in Sub-Acute Low Back Pain
- First Posted Date
- 2006-10-06
- Last Posted Date
- 2009-03-05
- Lead Sponsor
- United States Department of Defense
- Registration Number
- NCT00384371
- Locations
- 🇺🇸
Walter Reed Army Medical Center, Washington, District of Columbia, United States
Placebo Controlled Trial of Botulinum Toxin for Gastroparesis
- First Posted Date
- 2006-09-07
- Last Posted Date
- 2015-06-09
- Lead Sponsor
- Temple University
- Target Recruit Count
- 32
- Registration Number
- NCT00372970
- Locations
- 🇺🇸
Temple University Hospital, Philadelphia, Pennsylvania, United States
A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain
- Conditions
- First Posted Date
- 2006-06-13
- Last Posted Date
- 2011-07-26
- Lead Sponsor
- Taipei Medical University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT00336349
- Locations
- 🇨🇳
Chaur-Jong Hu, Taipei, Taiwan
Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.
- First Posted Date
- 2006-05-03
- Last Posted Date
- 2020-10-14
- Lead Sponsor
- Craig Hospital
- Target Recruit Count
- 19
- Registration Number
- NCT00320281
- Locations
- 🇺🇸
Craig Hospital, Englewood, Colorado, United States
Drug Development Updates
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