Botulinum toxin type A
- Generic Name
- Botulinum toxin type A
- Brand Names
- Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-43-1
- Unique Ingredient Identifier
- 0A6JH35GMQ
- Background
In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...
- Indication
Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
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- Associated Conditions
- Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis
- Associated Therapies
- -
Longitudinal Evaluation and Real-world Evidence of NT201
- Conditions
- Interventions
- First Posted Date
- 2022-02-03
- Last Posted Date
- 2023-06-07
- Lead Sponsor
- Merz North America, Inc.
- Target Recruit Count
- 11
- Registration Number
- NCT05222607
- Locations
- 🇺🇸
SkinDC, Arlington, Virginia, United States
Evolving Treatment Modalities for Management of Patients Suffering From Disc Displacement With Reduction
- Conditions
- Interventions
- First Posted Date
- 2022-01-18
- Last Posted Date
- 2023-12-04
- Lead Sponsor
- Nourhan M.Aly
- Target Recruit Count
- 27
- Registration Number
- NCT05194488
- Locations
- 🇪🇬
Faculty of Dentistry, Alexandria University, Alexandria, Egypt
Comparing Number of Injection Sites of In-office Intravesical Onabotulinumtoxin A Treatments for Overactive Bladder: A Randomized Controlled Trial
- First Posted Date
- 2021-12-15
- Last Posted Date
- 2021-12-15
- Lead Sponsor
- Augusta University
- Target Recruit Count
- 100
- Registration Number
- NCT05157295
A Study To Assess the Safety of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
- First Posted Date
- 2021-11-26
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- AbbVie
- Target Recruit Count
- 292
- Registration Number
- NCT05134649
- Locations
- 🇺🇸
Steve Yoelin MD Medical Assoc. Inc /ID# 232004, Newport Beach, California, United States
🇺🇸Susan H. Weinkle MD /ID# 232001, Bradenton, Florida, United States
🇺🇸Research Institute of the Southeast, LLC /ID# 231974, West Palm Beach, Florida, United States
Evaluation of Botox Treatment on Chronical Scrotal Pain
- Conditions
- Interventions
- First Posted Date
- 2021-11-08
- Last Posted Date
- 2022-04-20
- Lead Sponsor
- Nicolai Skov Schiellerup
- Target Recruit Count
- 50
- Registration Number
- NCT05112081
- Locations
- 🇩🇰
Odense University Hospital, Odense C, Fyn, Denmark
Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
- First Posted Date
- 2021-10-19
- Last Posted Date
- 2021-10-27
- Lead Sponsor
- Clinical Testing of Beverly Hills
- Target Recruit Count
- 40
- Registration Number
- NCT05083286
- Locations
- 🇺🇸
Steve Yoelin MD, Newport Beach, California, United States
🇺🇸Clinical Testing of Beverly Hills, Encino, California, United States
Longevity of Microwave Thermolysis and Botulinum Toxin A for Treatment of Axillary Hyperhidrosis
- Conditions
- Interventions
- First Posted Date
- 2021-09-27
- Last Posted Date
- 2023-05-26
- Lead Sponsor
- Merete Haedersdal
- Target Recruit Count
- 30
- Registration Number
- NCT05057117
- Locations
- 🇩🇰
Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark
A Study of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines
- First Posted Date
- 2021-08-19
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Allergan
- Target Recruit Count
- 92
- Registration Number
- NCT05013424
- Locations
- 🇺🇸
Etre Cosmetic Dermatology and Laser Center /ID# 227365, New Orleans, Louisiana, United States
🇺🇸Advanced Research Associates - Glendale /ID# 227368, Glendale, Arizona, United States
🇺🇸Austin Institute for Clinical Research /ID# 227367, Pflugerville, Texas, United States
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
- First Posted Date
- 2021-08-06
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- AbbVie
- Target Recruit Count
- 426
- Registration Number
- NCT04994535
- Locations
- 🇺🇸
Westside Aesthetics /ID# 231196, Los Angeles, California, United States
🇺🇸DeNova Research /ID# 231191, Chicago, Illinois, United States
🇺🇸Skin and Cancer Associates, LLP /ID# 231189, Miami, Florida, United States
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence
- First Posted Date
- 2021-07-02
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- AbbVie
- Target Recruit Count
- 408
- Registration Number
- NCT04949399
- Locations
- 🇺🇸
Laser and Skin Surgery Center of Indiana /ID# 229515, Indianapolis, Indiana, United States
🇺🇸Advanced Research Associates - Glendale /ID# 229256, Glendale, Arizona, United States
🇺🇸Clinical Testing of Beverly Hills /ID# 229946, Encino, California, United States
Drug Development Updates
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