Botulinum toxin type A

Generic Name
Botulinum toxin type A
Brand Names
Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva
Drug Type
Biotech
Chemical Formula
-
CAS Number
93384-43-1
Unique Ingredient Identifier
0A6JH35GMQ
Background

In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...

Indication

Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
...

Associated Conditions
Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis
Associated Therapies
-
Clinical Trials
Related News

Botulinum Toxin Relieves Anxiety, Depression and Sleep Disorderes in Patients With Blepharospasm

Early Phase 1
Conditions
Blepharospasm
Interventions
Drug: Botulinum toxin type A
First Posted Date
2021-06-25
Last Posted Date
2022-07-19
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Target Recruit Count
50
Registration Number
NCT04939909
Locations
🇨🇳

Juan Ye, Hangzhou, Zhejiang, China

Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis

First Posted Date
2021-06-11
Last Posted Date
2023-10-19
Lead Sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Target Recruit Count
42
Registration Number
NCT04922983
Locations
🇺🇸

Manhattan Physical Medicine and Rehabilitation, PLLC, Manhattan, New York, United States

Botulinum Toxin Type A for Cold Intolerance Secondary to Digital Amputations and Replantations: A Pilot Study

Phase 1
Conditions
Cold Intolerance
Interventions
Drug: Botulinum toxin type A
First Posted Date
2021-06-08
Last Posted Date
2022-08-24
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
28
Registration Number
NCT04917731
Locations
🇺🇸

MGH, Boston, Massachusetts, United States

Dysport Dose-Ranging Treatment of Platysmal Bands

Phase 1
Active, not recruiting
Conditions
Platysma Bands
Interventions
Drug: AbobotulinumtoxinA
First Posted Date
2021-05-13
Last Posted Date
2022-10-12
Lead Sponsor
Clinical Testing of Beverly Hills
Target Recruit Count
30
Registration Number
NCT04886167
Locations
🇺🇸

Clinical Testing of Beverly Hills, Encino, California, United States

Trip-Tox, Effectiveness of Triptans Before and After Onabotulinumtoxin A Treatment in Chronic Migraine

First Posted Date
2021-05-04
Last Posted Date
2021-10-04
Lead Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Target Recruit Count
100
Registration Number
NCT04871152
Locations
🇪🇸

Headache and Neuralgia Unit. Neurology Department. Hospital Santa Creu i Sant Pau, Barcelona, Spain

Management of Popeye Sign With Botulinum Toxin After Bicepstenotomy

First Posted Date
2021-02-11
Last Posted Date
2021-10-22
Lead Sponsor
AZ Delta
Target Recruit Count
20
Registration Number
NCT04750291
Locations
🇧🇪

AZ Delta, Roeselare, Belgium

Efficacy of OnabotulinumtoxinA in Migraine

Phase 2
Completed
Conditions
Migraine
Interventions
Drug: OnabotulinumtoxinA
First Posted Date
2020-10-08
Last Posted Date
2020-10-08
Lead Sponsor
IRCCS National Neurological Institute "C. Mondino" Foundation
Target Recruit Count
32
Registration Number
NCT04578782
Locations
🇮🇹

Headache Science Center, Pavia, Italy

Motor and Non-motor Symptoms in Cervical Dystonia

Conditions
Dystonia, Focal
First Posted Date
2020-09-23
Last Posted Date
2020-09-23
Lead Sponsor
University of Roma La Sapienza
Target Recruit Count
43
Registration Number
NCT04560101
Locations
🇮🇹

Department of Human Neurosciences, Rome, Italy

The Treatment of Shoulder Pain in Hemiplegic Spastic Patients With Botulinum Toxin A

Phase 4
Completed
Conditions
Shoulder Pain
Interventions
Drug: AbobotulinumtoxinA
Drug: Saline
First Posted Date
2020-07-14
Last Posted Date
2021-09-21
Lead Sponsor
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Target Recruit Count
24
Registration Number
NCT04470401
Locations
🇧🇷

Santa Casa SP, São Paulo, Sao Paulo, Brazil

Ultrasound Guided Botulinum Toxin Type A Injection of Subacromial-Subdeltoid Bursa in Hemiplegic Shoulder Pain

First Posted Date
2020-07-13
Last Posted Date
2020-10-08
Lead Sponsor
Benha University
Target Recruit Count
36
Registration Number
NCT04467450
Locations
🇪🇬

Eman, Banhā, Qalyubia, Egypt

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