MedPath

Menotropins

Generic Name
Menotropins
Brand Names
Menopur
Drug Type
Biotech
CAS Number
9002-68-0
Unique Ingredient Identifier
8FYM5179QJ
Background

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.

Indication

For the treatment of female infertility

Associated Therapies
Assisted Reproductive Technology therapy

Preimplantation Genetic Diagnosis (PGD) With Gonadotropin-releasing Hormone (GnRH) Agonist Versus Antagonist

Phase 4
Completed
Conditions
Reproductive Endocrinology
Fertility
Optimal Stimulation Protocol
Interventions
First Posted Date
2013-06-28
Last Posted Date
2013-06-28
Lead Sponsor
Universitair Ziekenhuis Brussel
Target Recruit Count
120
Registration Number
NCT01888744
Locations
🇧🇪

Centre for Reproductive Medicine, Brussels, Belgium

Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils

Not Applicable
Conditions
Hypertriglyceridaemia
Familial Hypercholesterolaemia
Interventions
Dietary Supplement: Fish oil capsule
First Posted Date
2012-04-13
Last Posted Date
2012-04-13
Lead Sponsor
The University of Western Australia
Target Recruit Count
30
Registration Number
NCT01577056
Locations
🇦🇺

School of Medicine & Pharmacology,University of Western Australia, Perth, Western Australia, Australia

Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur

Not Applicable
Completed
Conditions
Subfertility
Interventions
Drug: Clomifen, Ethinyl Estradiol
First Posted Date
2012-04-03
Last Posted Date
2014-09-10
Lead Sponsor
University Hospital, Gasthuisberg
Target Recruit Count
371
Registration Number
NCT01569945
Locations
🇧🇪

Leuven University Fertility Center, Leuven, Vlaams Brabant, Belgium

hMG or Recombinant FSH on OHSS Prevention in PCOS Patients Undergoing IVF

Phase 4
Completed
Conditions
Polycystic Ovary Syndrome
Interventions
Drug: rFSH
First Posted Date
2011-06-03
Last Posted Date
2012-03-29
Lead Sponsor
Zekai Tahir Burak Women's Health Research and Education Hospital
Target Recruit Count
80
Registration Number
NCT01365936
Locations
🇹🇷

Zekai Tahir Burak women's research and Training Hospital, Ankara, Turkey

Assessment of the Effectiveness of Menopur in Intrauterine Insemination

Completed
Conditions
Infertility
Interventions
First Posted Date
2011-05-17
Last Posted Date
2025-03-28
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
207
Registration Number
NCT01354834
Locations
🇪🇸

Investigational site, Valladolid, Spain

Time-lapse Evaluation of Embryo Development After Stimulation With One of Two Different Gonadotrophins.

Phase 4
Terminated
Conditions
Patients for In Vitro Fertilization(IVF)Treatment
Interventions
First Posted Date
2011-05-02
Last Posted Date
2012-09-14
Lead Sponsor
University of Aarhus
Target Recruit Count
291
Registration Number
NCT01345812
Locations
🇩🇰

The fertility clinic, Braedstrup, Denmark

Comparative Assessment of the Clinical Utility of Ovarian Stimulation With Menotropin Versus Menotropin Plus GnRH Antagonist

Completed
Conditions
Sterility
Interventions
First Posted Date
2011-04-08
Last Posted Date
2011-04-08
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
131
Registration Number
NCT01331733
Locations
🇪🇸

Investigational site, Valladolid, Spain

Safety and Efficacy Study in in Vitro Fertilisation (IVF) Patients

Phase 3
Completed
Conditions
Infertility
Interventions
First Posted Date
2011-03-11
Last Posted Date
2016-07-22
Lead Sponsor
IBSA Institut Biochimique SA
Target Recruit Count
270
Registration Number
NCT01312766
Locations
🇩🇰

Fertility clinic at Hvidovre Hospital, Hvidovre, Copenhagen, Denmark

🇬🇧

Midland Fertility Services, Aldridge, West Midlands, United Kingdom

🇩🇰

Odense Universitetshospital, Odense, Odensee C, Denmark

and more 3 locations

Progesterone Serum Levels in Subfertile Female Patients Undergoing in Vitro Fertilisation (IVF)

Phase 4
Completed
Conditions
Infertility
Interventions
First Posted Date
2010-10-21
Last Posted Date
2014-03-14
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
124
Registration Number
NCT01225835
Locations
🇩🇪

IVF Zentrum, Saar, Germany

🇩🇪

Endokrinologikum Ulm, Ulm, Germany

🇩🇪

Fertility Center Berlin, Berlin, Germany

and more 5 locations

Effect of a Higher Than Maximum 450IU Gonadotropin Dose in an In-vitro Fertilization Cycle

Phase 3
Completed
Conditions
Subfertility
Interventions
First Posted Date
2009-09-03
Last Posted Date
2014-03-13
Lead Sponsor
Clinique Ovo
Target Recruit Count
366
Registration Number
NCT00971152
Locations
🇨🇦

Ovo Fertilité, Montreal, Quebec, Canada

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