Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...

Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Clinical Trials
Related News

Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic

Phase 2
Completed
Conditions
Postoperative Pain
Interventions
Drug: Bupivacaine
First Posted Date
2012-08-10
Last Posted Date
2013-07-02
Lead Sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Target Recruit Count
66
Registration Number
NCT01662401
Locations
🇺🇸

Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty

First Posted Date
2012-07-10
Last Posted Date
2014-07-28
Lead Sponsor
Mahidol University
Target Recruit Count
43
Registration Number
NCT01636869
Locations
🇹🇭

Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Pathophysiology of Post Amputation Pain

Phase 4
Completed
Conditions
Amputation Stumps
Neuroma
Interventions
Drug: Placebo
Drug: Bupivacaine
First Posted Date
2012-07-03
Last Posted Date
2015-07-21
Lead Sponsor
Shirley Ryan AbilityLab
Target Recruit Count
16
Registration Number
NCT01632709
Locations
🇺🇸

Rehabilitation Institute of Chicago, Chicago, Illinois, United States

Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study

First Posted Date
2012-06-12
Last Posted Date
2015-02-04
Lead Sponsor
Case Western Reserve University
Target Recruit Count
200
Registration Number
NCT01616992
Locations
🇺🇸

Summa Health System, Akron, Ohio, United States

🇺🇸

University Hospitals Case Medical Center, Cleveland, Ohio, United States

A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block

Phase 4
Terminated
Conditions
Fracture of Foot
Interventions
Drug: Bupivacaine
Drug: Ropivacaine
First Posted Date
2012-06-11
Last Posted Date
2016-08-01
Lead Sponsor
Northwestern University
Target Recruit Count
17
Registration Number
NCT01615939
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

Bupivacaine Injection of Eye Muscles to Treat Strabismus

First Posted Date
2012-06-11
Last Posted Date
2019-09-23
Lead Sponsor
Smith-Kettlewell Eye Research Institute
Target Recruit Count
120
Registration Number
NCT01616108
Locations
🇺🇸

Strabismus Research Foundation, San Francisco, California, United States

Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain

Phase 2
Terminated
Conditions
Chronic Pain
Interventions
Drug: Placebo
Drug: Bupivacaine
First Posted Date
2012-04-25
Last Posted Date
2016-02-19
Lead Sponsor
Hvidovre University Hospital
Target Recruit Count
31
Registration Number
NCT01584947
Locations
🇩🇰

Department of Odontology, University of Copenhagen, Copenhagen, Denmark

Voiding Function After Mid-Urethral Slings With and Without Local Anesthetic: Randomized Controlled Trial

First Posted Date
2012-04-23
Last Posted Date
2018-11-28
Lead Sponsor
University of Massachusetts, Worcester
Target Recruit Count
90
Registration Number
NCT01583166
Locations
🇺🇸

University of Massachusetts, Worcester, Massachusetts, United States

Evaluation of The Effect of Bupivacaine (Marcaine) in Reducing Early Post Tonsillectomy Pain

First Posted Date
2012-04-20
Last Posted Date
2012-04-20
Lead Sponsor
King Saud University
Registration Number
NCT01582022

Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies

Phase 2
Terminated
Conditions
Appendicitis
Interventions
Drug: Bupivacaine
Drug: Ropivacaine
First Posted Date
2012-04-10
Last Posted Date
2015-08-24
Lead Sponsor
Nationwide Children's Hospital
Target Recruit Count
3
Registration Number
NCT01575028
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy