Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Repair
- First Posted Date
- 2010-09-16
- Last Posted Date
- 2021-01-25
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 76
- Registration Number
- NCT01203644
The Effects of Anesthetic Method on Cerebral Oxygen Saturation in Geriatric Patients Undergoing Transurethral Surgery
- Conditions
- First Posted Date
- 2010-06-22
- Last Posted Date
- 2011-05-13
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 64
- Registration Number
- NCT01147146
- Locations
- 🇰🇷
Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of
Pain Relief at Iliac Crest Bone Harvest Sites in Spine Surgery Using Bupivacaine
- First Posted Date
- 2010-03-16
- Last Posted Date
- 2018-06-25
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 40
- Registration Number
- NCT01087931
- Locations
- 🇺🇸
Vanderbilt Medical Center, Nashville, Tennessee, United States
Bupivacaine Versus Lidocaine on Inflammatory Regulation
- First Posted Date
- 2010-02-02
- Last Posted Date
- 2018-05-31
- Lead Sponsor
- University of Maryland
- Target Recruit Count
- 11
- Registration Number
- NCT01060774
- Locations
- 🇺🇸
University of Maryland, Baltimore College of Dental Surgery, Baltimore, Maryland, United States
Bupivacaine Effectiveness and Safety in SABER® Trial
- Conditions
- Interventions
- First Posted Date
- 2010-01-20
- Last Posted Date
- 2021-06-01
- Lead Sponsor
- Durect
- Target Recruit Count
- 331
- Registration Number
- NCT01052012
- Locations
- 🇳🇿
DURECT Study Site, Christchurch, New Zealand
Management of Postoperative Pain After Total Hip Arthroplasty
- First Posted Date
- 2009-12-29
- Last Posted Date
- 2009-12-29
- Lead Sponsor
- Chang Gung Memorial Hospital
- Registration Number
- NCT01040273
- Locations
- 🇨🇳
Chang Gung Memorial Hospital, Kweishian, Taoyuan, Taiwan
Transversus Abdominis Plane (TAP) Block for Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2009-11-18
- Last Posted Date
- 2017-10-23
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 90
- Registration Number
- NCT01015807
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
🇧🇷Hospital e Maternidade Santa Joana, São Paulo, Brazil
Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE
- First Posted Date
- 2009-11-01
- Last Posted Date
- 2017-11-08
- Lead Sponsor
- Wake Forest University
- Target Recruit Count
- 46
- Registration Number
- NCT01005459
- Locations
- 🇺🇸
Forsyth Medical Center- OB Anesthesia dept, Winston-Salem, North Carolina, United States
Different Approaches to Maternal Hypotension During Cesarean Section
- First Posted Date
- 2009-10-08
- Last Posted Date
- 2010-08-27
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 36
- Registration Number
- NCT00991627
- Locations
- 🇮🇹
University and Hospital of Parma (Azienda Ospedaliero-Universitaria di Parma), Parma, PR, Italy
Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean Section
- Conditions
- Interventions
- First Posted Date
- 2009-06-16
- Last Posted Date
- 2009-06-16
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 216
- Registration Number
- NCT00921102
- Locations
- 🇮🇹
University and Hospital of Parma (Azienda Ospedaliero-Universitaria di Parma), Parma, PR, Italy
🇮🇹University of Messina, Messina, ME, Italy
Drug Development Updates
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