Pentoxifylline
- Generic Name
- Pentoxifylline
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18N4O3
- CAS Number
- 6493-05-6
- Unique Ingredient Identifier
- SD6QCT3TSU
- Background
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties. Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated...
- Indication
Pentoxifylline is indicated for the treatment of intermittent claudication in patients with chronic occlusive arterial disease. Pentoxifylline may improve limb function and reduce symptoms but cannot replace other therapies such as surgical bypass or removal of vascular obstructions.
- Associated Conditions
- Intermittent Claudication, Venous Leg Ulcer (VLU), Severe alcoholic liver disease
- Associated Therapies
- -
Combined Microneedling and Topical Pentoxifylline Vesrus Intalesional Pentoxifylline in Treatment of Alopecia Areata: Intra-indiviual Comparative Study
- First Posted Date
- 2022-08-16
- Last Posted Date
- 2022-08-16
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 50
- Registration Number
- NCT05502952
- Locations
- 🇪🇬
Sohag University Hospital, Sohag, Egypt
Enhancing Effect on Tumour Apoptosis With the Use of Pentoxifylline in Patients With Hodgkin Lymphoma
- First Posted Date
- 2022-08-08
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- University of Guadalajara
- Target Recruit Count
- 30
- Registration Number
- NCT05490953
- Locations
- 🇲🇽
Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico
Evaluate the Effect and Safety of Pu Yang Wan Wu Tang and Western Medicine on Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2022-05-24
- Last Posted Date
- 2023-06-26
- Lead Sponsor
- Taipei Medical University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT05387187
- Locations
- 🇨🇳
Taipei Medical University, Taipei, Taiwan
Efficacy and Safety of Pentoxifylline in Improving Oxygenation in Hepatopulmonary Syndrome
- First Posted Date
- 2022-05-13
- Last Posted Date
- 2022-05-13
- Lead Sponsor
- Institute of Liver and Biliary Sciences, India
- Target Recruit Count
- 40
- Registration Number
- NCT05373134
- Locations
- 🇮🇳
Institute of Liver & Biliary Sciences, New Delhi, Delhi, India
Pentoxifylline for Treatment of Resistant Major Depression
- First Posted Date
- 2022-04-12
- Last Posted Date
- 2022-09-07
- Lead Sponsor
- Hawler Medical University
- Target Recruit Count
- 60
- Registration Number
- NCT05324735
- Locations
- 🇮🇶
Hawler Psychiatric Hospital and Private Clinic, Erbil, Iraq
"Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients"
- Conditions
- Interventions
- First Posted Date
- 2022-01-12
- Last Posted Date
- 2024-01-23
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 66
- Registration Number
- NCT05189535
- Locations
- 🇪🇬
Ain Shams University hospitals, Cairo, Abbasia, Egypt
The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia
- Conditions
- Interventions
- First Posted Date
- 2022-01-05
- Last Posted Date
- 2022-01-05
- Lead Sponsor
- Arak University of Medical Sciences
- Target Recruit Count
- 160
- Registration Number
- NCT05178953
- Locations
- 🇮🇷
Arak university of medical science, Arak, Markazi, Iran, Islamic Republic of
🇮🇷Infertility Center, Arak, Markazi, Iran, Islamic Republic of
Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia
- Conditions
- Interventions
- First Posted Date
- 2021-12-14
- Last Posted Date
- 2022-01-03
- Lead Sponsor
- Arak University of Medical Sciences
- Target Recruit Count
- 140
- Registration Number
- NCT05156684
Comparing the Effects of Vitamin E, Ursodeoxycholic Acid and Pentoxyfylline on Egyptian Non-alcoholic Steatohepatitis (NASH) Patients
- Conditions
- Interventions
- First Posted Date
- 2021-07-27
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 102
- Registration Number
- NCT04977661
- Locations
- 🇪🇬
Hepatology, gastroenterology and infectious diseases department at Kafrelsheikh University Hospital, Cairo, Egypt
Effect of Pentoxifylline on Prognosis of Coronavirus Disease 2019 (COVID- 19) Infection
- Conditions
- Interventions
- First Posted Date
- 2021-02-04
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 69
- Registration Number
- NCT04739345
- Locations
- 🇪🇬
Teachers Hospital, Cairo, Please Select, Egypt
Drug Development Updates
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