Riboflavin
- Generic Name
- Riboflavin
- Brand Names
- Alertonic, Concept Ob, Irospan 24/6 Kit, Mvc-fluoride, Natafort, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C17H20N4O6
- CAS Number
- 83-88-5
- Unique Ingredient Identifier
- TLM2976OFR
- Background
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
- Indication
For the treatment of ariboflavinosis (vitamin B2 deficiency).
- Associated Conditions
- Ariboflavinosis, Beriberi, Constipation, Functional Gastrointestinal Disorders (FGID), Joint Pain, Metabolic cardiomyopathy, Migraine, Myalgia, Neuropathic Pain, Peripheral neuritis, Peripheral paralysis, Vitamin B complex deficiency, Vitamin B1 deficiency, Vitamin Deficiency, Wernicke's encephalopathy
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation, Vitamin supplementation, Dietary supplementation
Safety Study of the VEGA UV-A System to Treat Ectasia
- Conditions
- Ectasia
- Interventions
- Device: VEGA UV-A Illumination System
- First Posted Date
- 2011-07-21
- Last Posted Date
- 2022-06-29
- Lead Sponsor
- Topcon Medical Systems, Inc.
- Target Recruit Count
- 103
- Registration Number
- NCT01398839
- Locations
- 🇺🇸
Barnet Dulaney Perkins Eye Center, Phoenix, Arizona, United States
🇺🇸Slade & Baker Vision, Houston, Texas, United States
🇺🇸The Eye Institute of Utah, Salt Lake City, Utah, United States
Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus
- Conditions
- Keratoconus
- Interventions
- First Posted Date
- 2011-04-29
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Glaukos Corporation
- Target Recruit Count
- 236
- Registration Number
- NCT01344187
- Locations
- 🇺🇸
Vance Thompson Vision, Sioux Falls, South Dakota, United States
🇺🇸Medical University of South Carolina Storm Eye Institute, Magill Vision Center, Mount Pleasant, South Carolina, United States
🇺🇸Emory Eye Center, Atlanta, Georgia, United States
UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia
- First Posted Date
- 2011-03-29
- Last Posted Date
- 2011-03-29
- Lead Sponsor
- Mercy Center for Corrective Eye Surgery
- Target Recruit Count
- 250
- Registration Number
- NCT01325298
- Locations
- 🇺🇸
Mercy Center for Corrective Eye Surgery, McHenry, Illinois, United States
Riboflavin Corneal Crosslinking for Brittle Cornea Syndrome and Ehlers-Danlos Syndrome Type VI
- Conditions
- Brittle Cornea SyndromeEhlers-Danlos Syndrome Type 6
- First Posted Date
- 2011-03-03
- Last Posted Date
- 2011-03-03
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 1
- Registration Number
- NCT01307527
- Locations
- 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel
Safety Study of the VEGA UV-A System to Treat Keratoconus
- Conditions
- Keratoconus
- Interventions
- Device: The VEGA UV-A Illumination System
- First Posted Date
- 2010-08-27
- Last Posted Date
- 2022-07-12
- Lead Sponsor
- Topcon Medical Systems, Inc.
- Target Recruit Count
- 127
- Registration Number
- NCT01190306
- Locations
- 🇺🇸
Woolfson Eye Institute, Atlanta, Georgia, United States
🇺🇸Barnet Dulaney Perkins Eye Center, Phoenix, Arizona, United States
🇺🇸Minnesota Eye Consultants, Bloomington, Minnesota, United States
Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin
- Conditions
- KeratoconusCorneal Ectasia
- Interventions
- Drug: Riboflavin/Dextran
- First Posted Date
- 2010-06-29
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Cornea and Laser Eye Institute
- Target Recruit Count
- 160
- Registration Number
- NCT01152541
- Locations
- 🇺🇸
Cornea and Laser Eye Institute, Teaneck, New Jersey, United States
Corneal Crosslinking in Patients With Keratoconus and Post-Refractive Ectasia
- Conditions
- KeratoconusPost-Refractive Ectasia
- Interventions
- Device: UVX light
- First Posted Date
- 2010-06-14
- Last Posted Date
- 2018-06-06
- Lead Sponsor
- Price Vision Group
- Target Recruit Count
- 510
- Registration Number
- NCT01143389
- Locations
- 🇺🇸
Price Vision Group, Indianapolis, Indiana, United States
Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia
- First Posted Date
- 2010-04-28
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Cornea and Laser Eye Institute
- Target Recruit Count
- 160
- Registration Number
- NCT01112072
- Locations
- 🇺🇸
Cornea and Laser Eye Institute, Teaneck, New Jersey, United States
Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs
- First Posted Date
- 2010-03-05
- Last Posted Date
- 2018-10-02
- Lead Sponsor
- Yaron S. Rabinowitz M.D.
- Target Recruit Count
- 600
- Registration Number
- NCT01081561
- Locations
- 🇺🇸
Cornea Eye Institute, 50 North La Cienaga Blvd, #340, Beverly Hills, California, United States
Cross Linking for Treatment of Corneal Infection
- Conditions
- Infectious Keratitis
- Interventions
- Device: UVX Light
- First Posted Date
- 2009-06-03
- Last Posted Date
- 2017-11-22
- Lead Sponsor
- Price Vision Group
- Target Recruit Count
- 30
- Registration Number
- NCT00912509
- Locations
- 🇺🇸
Price Vision Group, Indianapolis, Indiana, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.