Cefazolin
- Generic Name
- Cefazolin
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14N8O4S3
- CAS Number
- 25953-19-9
- Unique Ingredient Identifier
- IHS69L0Y4T
- Background
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
- Indication
Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis; if required metronidazole may be added to cover B. fragilis.
- Associated Conditions
- Bacterial Septicemia caused by susceptible Bacterial Infections, Biliary tract infection bacterial caused by susceptible Bacterial Infections, Bone and Joint Infections caused by susceptible Bacterial Infections, Catheter-related Bloodstream Infection (CRBSI) NOS, Community Acquired Pneumonia (CAP), Endocarditis caused by susceptible Bacterial Infections, Genital infection caused by susceptible Bacterial Infections, Osteoarticular Infections, Postoperative Infections, Respiratory Tract Infection Bacterial caused by susceptible Bacterial Infections, Skin and Soft Tissue Infections (SSTIs), Skin and Subcutaneous Tissue Infection caused by susceptible Bacterial Infections, Susceptible infections, Urinary Tract Infection caused by susceptible Bacterial Infections, Perioperative infection, Susceptible Bacterial Infections
- Associated Therapies
- Antibiotic pre-surgical prophylaxis
Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 56
- Registration Number
- NCT03115177
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI)
- Conditions
- Knee Arthropathy
- Interventions
- First Posted Date
- 2017-03-29
- Last Posted Date
- 2024-12-27
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 86
- Registration Number
- NCT03094663
- Locations
- 🇺🇸
Hospital For Special Surgery, New York, New York, United States
Peritonitis Prevention After Insertion of Peritoneal Dialysis Catheter.
- Conditions
- Peritoneal Dialysis ComplicationPeritoneal Dialysis Catheter InfectionPeritoneal Dialysis-associated Peritonitis
- Interventions
- First Posted Date
- 2017-02-08
- Last Posted Date
- 2023-02-13
- Lead Sponsor
- Carmel Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT03046511
- Locations
- 🇮🇱
Carmel Medical Center, Haifa, Israel
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
- Conditions
- Propionibacterium Infection
- Interventions
- First Posted Date
- 2016-12-19
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Université de Montréal
- Target Recruit Count
- 88
- Registration Number
- NCT02996656
- Locations
- 🇨🇦
Hôpital du Sacré-Cœur de Montréal, Montréal, Quebec, Canada
Comparing Cefepime Versus Cefazolin Plus Ceftazidime for CAPD-associated Peritonitis
- Conditions
- Peritoneal Dialysis Associated Peritonitis
- Interventions
- First Posted Date
- 2016-08-18
- Last Posted Date
- 2017-10-31
- Lead Sponsor
- Chulalongkorn University
- Target Recruit Count
- 154
- Registration Number
- NCT02872038
- Locations
- 🇹🇭
Chulalongkorn University, Bangkok, Thailand
Preventive Antibiotic Serum Levels During Caesarean Section
- First Posted Date
- 2016-07-20
- Last Posted Date
- 2016-07-20
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 250
- Registration Number
- NCT02838940
Antibiotic Prophylaxis in Oncological Surgery of Breast
- Conditions
- Breast NeoplasmsBreast-Conserving SurgeryWound InfectionAntibiotic Prophylaxis
- Interventions
- First Posted Date
- 2016-06-22
- Last Posted Date
- 2017-10-25
- Lead Sponsor
- Fabiola Soares Moreira Campos
- Target Recruit Count
- 124
- Registration Number
- NCT02809729
- Locations
- 🇧🇷
Universidade Do Vale Do Sapucai, Pouso Alegre, Minas Gerais, Brazil
Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis
- Conditions
- Keratitis; Infectious Disease (Manifestation)
- Interventions
- Device: PACK-CXLDrug: Cycloplegic agents (cyclopentolate 1% eye drops)Drug: Corticosteroids (prednisolone acetate 0.5% or 1% eye drops)
- First Posted Date
- 2016-03-24
- Last Posted Date
- 2020-10-20
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 35
- Registration Number
- NCT02717871
- Locations
- 🇨🇭
University of Geneva, Geneva, GE, Switzerland
Prophylactic Antibiotics Before RFA for HCC
- First Posted Date
- 2015-08-28
- Last Posted Date
- 2015-08-28
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 600
- Registration Number
- NCT02534961
- Locations
- 🇨🇳
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
The Effect of Bowel Preparation on Perioperative Bleeding
- First Posted Date
- 2015-07-10
- Last Posted Date
- 2015-07-10
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 105
- Registration Number
- NCT02493894
- Locations
- 🇮🇷
Alzahra Hospital, Isfahan, Iran, Islamic Republic of
Drug Development Updates
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