Cefazolin

Generic Name
Cefazolin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C14H14N8O4S3
CAS Number
25953-19-9
Unique Ingredient Identifier
IHS69L0Y4T
Background

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Indication

Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylax...

Associated Conditions
Bacterial Septicemia caused by susceptible Bacterial Infections, Biliary tract infection bacterial caused by susceptible Bacterial Infections, Bone and Joint Infections caused by susceptible Bacterial Infections, Catheter-related Bloodstream Infection (CRBSI) NOS, Community Acquired Pneumonia (CAP), Endocarditis caused by susceptible Bacterial Infections, Genital infection caused by susceptible Bacterial Infections, Osteoarticular Infections, Postoperative Infections, Respiratory Tract Infection Bacterial caused by susceptible Bacterial Infections, Skin and Soft Tissue Infections (SSTIs), Skin and Subcutaneous Tissue Infection caused by susceptible Bacterial Infections, Susceptible infections, Urinary Tract Infection caused by susceptible Bacterial Infections, Perioperative infection, Susceptible Bacterial Infections
Associated Therapies
Antibiotic pre-surgical prophylaxis
Clinical Trials
Related News

Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis

Phase 4
Withdrawn
Conditions
Endometritis
Interventions
Drug: Azithromycin
Drug: Cefazolin
First Posted Date
2012-11-06
Last Posted Date
2015-05-05
Lead Sponsor
University of Missouri, Kansas City
Registration Number
NCT01721616
Locations
🇺🇸

Truman Medical Center - Hospital Hill, Kansas City, Missouri, United States

Prevention of Arrhythmia Device Infection Trial (PADIT)

Phase 4
Completed
Conditions
Arrhythmia
Interventions
Drug: Incremental
Drug: Cefazolin
First Posted Date
2012-06-06
Last Posted Date
2014-10-10
Lead Sponsor
Population Health Research Institute
Target Recruit Count
241
Registration Number
NCT01613092
Locations
🇨🇦

University of Ottawa Heart Institute, Ottawa, Ontario, Canada

🇨🇦

Hamilton General Hospital, McMaster University, Hamilton, Ontario, Canada

Tissue and Plasma Pharmacokinetics of Cefazolin in Antibiotic Prophylaxis in Bariatric Surgery

Phase 4
Completed
Conditions
Bariatric Surgery
Interventions
Drug: Cefazoline
First Posted Date
2012-02-23
Last Posted Date
2017-07-19
Lead Sponsor
Nantes University Hospital
Target Recruit Count
117
Registration Number
NCT01537380
Locations
🇫🇷

Nantes University Hospital, Nantes, France

Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane

First Posted Date
2012-01-04
Last Posted Date
2022-04-20
Lead Sponsor
Samsung Medical Center
Target Recruit Count
151
Registration Number
NCT01503606
Locations
🇰🇷

Samsung Medical center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of

Cefazolin Pharmacokinetics: Elimination Clearance in Neonates

Phase 4
Completed
Conditions
Prophylaxis
Interventions
Drug: Cefazolin
First Posted Date
2011-02-14
Last Posted Date
2011-12-13
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
40
Registration Number
NCT01295606

Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair

First Posted Date
2011-01-11
Last Posted Date
2014-12-29
Lead Sponsor
Diskapi Teaching and Research Hospital
Target Recruit Count
276
Registration Number
NCT01273818
Locations
🇹🇷

Diskapi Yildirim Beyazit Teaching and research Hospital, Ankara, Turkey

Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion

First Posted Date
2010-11-10
Last Posted Date
2018-10-23
Lead Sponsor
Sonescence, Inc.
Registration Number
NCT01238276
Locations
🇺🇸

Sonoma West Medical Center, Sebastopol, California, United States

Prevention of Arrhythmia Device Infection Trial (PADIT Pilot)

First Posted Date
2009-10-28
Last Posted Date
2013-05-16
Lead Sponsor
Population Health Research Institute
Target Recruit Count
500
Registration Number
NCT01002911
Locations
🇨🇦

Institut universitaire de cardiologie et de pneumologie de Quebec, Ste-Foy, Quebec, Canada

An Open Label Study to Describe the Pharmacokinetics of Cefazolin in Preterm Neonates

Phase 1
Completed
Conditions
Sepsis
Prematurity
Interventions
Drug: cefazolin
First Posted Date
2009-02-24
Last Posted Date
2018-09-04
Lead Sponsor
Phillip Brian Smith
Target Recruit Count
9
Registration Number
NCT00850122
Locations
🇧🇷

Federal University of Sao Paulo, Sao Paulo, Brazil

Tinidazole Versus Cefazolin Antibiotic Prophylaxis of Vaginal and Abdominal Hysterectomy

First Posted Date
2008-11-07
Last Posted Date
2008-11-07
Lead Sponsor
University of Campinas, Brazil
Target Recruit Count
75
Registration Number
NCT00787553
Locations
🇧🇷

University of Campinas, Campinas, SP, Brazil

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy