Capsaicin

Generic Name
Capsaicin
Brand Names
Capzasin Quick Relief, Capzasin-HP, Castiva Warming, Dendracin Neurodendraxcin, Lidopro, Medi-derm, Medi-derm With Lidocaine, Medrox, Qutenza, Rematex, Xoten-C, Zostrix
Drug Type
Small Molecule
Chemical Formula
C18H27NO3
CAS Number
404-86-4
Unique Ingredient Identifier
S07O44R1ZM
Background

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent capsaicin F...

Indication

The capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.

Associated Conditions
Back Pain Lower Back, Back pain, Bursitis, Contusions, Inflammatory Reaction caused by Rheumatism, Muscle Cramps, Musculoskeletal Pain, Neuropathic Pain, Osteoarthritis (OA), Pain caused by Rheumatism, Periarthritis, Soft Tissue Injury, Tendinitis, Acute nonspecific tenosynovitis, Articular inflammation
Associated Therapies
-
Clinical Trials
Related News

Capsaicin + Diclofenac Gel in Acute Back Pain or Neck Pain

Phase 3
Completed
Conditions
Acute Pain
Interventions
Drug: Placebo
Drug: Diclofenac
Drug: Capsaicin
First Posted Date
2016-03-07
Last Posted Date
2019-05-06
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
746
Registration Number
NCT02700815
Locations
🇩🇪

Anästhesiologie Rheinbach, Rheinbach, Germany

🇩🇪

Praxis Dr. Schaefer, 45355 Essen, Essen, Germany

🇩🇪

Dünnwaldpraxis, Köln, Köln, Germany

and more 12 locations

Experimental Biomarker Study for Pain Thresholds

First Posted Date
2016-03-01
Last Posted Date
2016-03-01
Lead Sponsor
Purdue Pharma LP
Target Recruit Count
37
Registration Number
NCT02695745
Locations
🇩🇰

CCBR A/S, Aalborg, Denmark

Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis

Phase 2
Completed
Conditions
Nonallergic Irritant Rhinitis
Interventions
Drug: Placebo
Drug: Capsaicin
First Posted Date
2015-07-09
Last Posted Date
2020-08-17
Lead Sponsor
The University of Texas Health Science Center, Houston
Target Recruit Count
22
Registration Number
NCT02493257
Locations
🇺🇸

The University of Texas Health Science Center at Houston, Houston, Texas, United States

Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia

Not Applicable
Completed
Conditions
Chest Pain
Interventions
Drug: Capsaicin
First Posted Date
2015-01-27
Last Posted Date
2021-03-04
Lead Sponsor
Bassett Healthcare
Target Recruit Count
22
Registration Number
NCT02346916
Locations
🇺🇸

Bassett Healthcare Network, Cooperstown, New York, United States

Chest Pain Perception and Capsaicin Sensitivity

Not Applicable
Completed
Conditions
Chest Pain
Interventions
Drug: Capsaicin
First Posted Date
2015-01-27
Last Posted Date
2021-03-04
Lead Sponsor
Bassett Healthcare
Target Recruit Count
99
Registration Number
NCT02346903
Locations
🇺🇸

Bassett Healthcare Network, Cooperstown, New York, United States

Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis

Phase 4
Completed
Conditions
Non-allergic Rhinitis
Interventions
Drug: placebo
Drug: Capsaicin
First Posted Date
2014-11-11
Last Posted Date
2021-06-22
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
80
Registration Number
NCT02288156
Locations
🇧🇪

ORL, Leuven, Vlaams-Brabant, Belgium

Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease

First Posted Date
2014-07-08
Last Posted Date
2017-03-24
Lead Sponsor
University of Florida
Target Recruit Count
44
Registration Number
NCT02183519
Locations
🇺🇸

Dauer Hall, University of Florida, Gainesville, Florida, United States

🇺🇸

Center for Movement Disorders and Neurorestoration, Gainesville, Florida, United States

Efficacy of Topical Capsaicin Cream for Stable Angina

Phase 3
Terminated
Conditions
Stable Angina
Interventions
Drug: Capsaicin
Other: Placebo cream
First Posted Date
2010-11-01
Last Posted Date
2015-06-25
Lead Sponsor
Neal Weintraub
Target Recruit Count
7
Registration Number
NCT01231750
Locations
🇺🇸

University of Cincinnati Physicians, Inc, Cincinnati, Ohio, United States

Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.

First Posted Date
2010-10-19
Last Posted Date
2011-10-03
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
36
Registration Number
NCT01223820
Locations
🇧🇪

UZ Leuven, NKO-GH Kapucijnenvoer 33, Leuven, Vlaams-Brabant, Belgium

Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy

Phase 2
Completed
Conditions
Diabetic Polyneuropathy
Interventions
Drug: Capsaicin
Drug: placebo
First Posted Date
2009-10-09
Last Posted Date
2012-05-09
Lead Sponsor
Thammasat University
Target Recruit Count
33
Registration Number
NCT00993070
Locations
🇹🇭

Thammasat University Hospital, Pathumthani, Thailand

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