Capsaicin

Generic Name
Capsaicin
Brand Names
Capzasin Quick Relief, Capzasin-HP, Castiva Warming, Dendracin Neurodendraxcin, Lidopro, Medi-derm, Medi-derm With Lidocaine, Medrox, Qutenza, Rematex, Xoten-C, Zostrix
Drug Type
Small Molecule
Chemical Formula
C18H27NO3
CAS Number
404-86-4
Unique Ingredient Identifier
S07O44R1ZM
Background

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent capsaicin F...

Indication

The capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.

Associated Conditions
Back Pain Lower Back, Back pain, Bursitis, Contusions, Inflammatory Reaction caused by Rheumatism, Muscle Cramps, Musculoskeletal Pain, Neuropathic Pain, Osteoarthritis (OA), Pain caused by Rheumatism, Periarthritis, Soft Tissue Injury, Tendinitis, Acute nonspecific tenosynovitis, Articular inflammation
Associated Therapies
-
Clinical Trials
Related News

Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain

Phase 2
Withdrawn
Conditions
Myofascial Pain Syndrome
Interventions
Drug: Placebo
Drug: Capsaicin
First Posted Date
2008-11-21
Last Posted Date
2016-12-06
Lead Sponsor
Stamford Hospital
Registration Number
NCT00795106
Locations
🇺🇸

Stamford Hospital, Stamford, Connecticut, United States

Cervical Capsaicin for Labor Induction and Pain Relief

First Posted Date
2008-10-13
Last Posted Date
2021-08-09
Lead Sponsor
Columbia University
Registration Number
NCT00771511

Effects of Capsaicin on the Structure, Distribution, and Function of Cutaneous Small Nerve Fibers in Psoriatic Skin

Phase 4
Terminated
Conditions
Psoriasis
Interventions
Drug: Capsaicin
First Posted Date
2008-06-13
Last Posted Date
2018-08-13
Lead Sponsor
Wake Forest University
Target Recruit Count
12
Registration Number
NCT00697034
Locations
🇺🇸

Wake Forest University Health Sciences Dermatology, Winston-Salem, North Carolina, United States

Effect of Spinal Ketorolac After Acute Opioid Exposure

First Posted Date
2008-06-06
Last Posted Date
2018-09-07
Lead Sponsor
Wake Forest University
Target Recruit Count
30
Registration Number
NCT00693160
Locations
🇺🇸

Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects

Phase 4
Completed
Conditions
Healthy
Interventions
Drug: Placebo moisturizing cream
Drug: Capsaicin
First Posted Date
2008-04-10
Last Posted Date
2018-09-10
Lead Sponsor
Wake Forest University
Target Recruit Count
40
Registration Number
NCT00655811
Locations
🇺🇸

Wake Forest University Health Sciences Dermatology, Winston-Salem, North Carolina, United States

Sensory Function After Wound Instillation of Capsaicin

Completed
Conditions
Primary Hyperalgesia
Interventions
Drug: Capsaicin
First Posted Date
2007-12-31
Last Posted Date
2008-01-30
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
42
Registration Number
NCT00583180
Locations
🇩🇰

Hørshol Sygehus, Hørsholm, Denmark

Response of Topical Capsaicin in Alopecia Areata

Phase 4
Completed
Conditions
Alopecia Areata
First Posted Date
2005-09-15
Last Posted Date
2014-06-02
Lead Sponsor
University of Minnesota
Target Recruit Count
24
Registration Number
NCT00176969
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Completed
Conditions
Healthy Volunteers
First Posted Date
2005-09-09
Last Posted Date
2017-11-01
Lead Sponsor
University Hospital, Angers
Target Recruit Count
85
Registration Number
NCT00152724
Locations
🇫🇷

Laboratoire de Physiologie et Explorations Vasculaires - CHU Angers, Angers, France

Capsaicin to Control Pain Following Third Molar Extraction

Phase 2
Completed
Conditions
Facial Pain
First Posted Date
2001-01-10
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Target Recruit Count
162
Registration Number
NCT00008476
Locations
🇺🇸

National Institute of Dental And Craniofacial Research (NIDCR), Bethesda, Maryland, United States

Positron Emission Tomography to Measure Pain and Pain Control

First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Target Recruit Count
273
Registration Number
NCT00001307
Locations
🇺🇸

National Institute of Dental And Craniofacial Research (NIDCR), Bethesda, Maryland, United States

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