DeepMed Research

MASSACHUSETTS EYE AND EAR INFIRMARY

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1824-01-01

Employees: -

Market Cap: -

Website: http://www.masseyeandear.org/

Clinical Trials

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

Phase 1

Completed

Conditions: Limbal Stem Cell Deficiency

Interventions: Procedure: Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft
Biological: Cultivation of Limbal epithelial cells into a graft
Procedure: CALEC Transplant

First Posted Date: 2015-10-30

Last Posted Date: 2025-01-15

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 23

Registration Number: NCT02592330

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients

Conditions: Neurofibromatosis Type 2
Severe Profound Sensorineural Hearing Loss

First Posted Date: 2015-10-28

Last Posted Date: 2019-12-06

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Registration Number: NCT02589912

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

Early Phase 1

Terminated

Conditions: Vestibular Schwannoma
Meningioma
Acoustic Neuroma
Neurofibromatosis Type 2

Interventions: Drug: AR-42

First Posted Date: 2014-11-05

Last Posted Date: 2022-05-11

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 7

Registration Number: NCT02282917

Locations: 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸
Stanford University, Stanford, California, United States
🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

and more 1 locations

Use of Amplification in Children With Unilateral Hearing Loss

Not Applicable

Completed

Conditions: Unilateral Hearing Loss

Interventions: Device: Hearing aid

First Posted Date: 2014-10-20

Last Posted Date: 2021-08-11

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 37

Registration Number: NCT02269124

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation

Phase 4

Terminated

Conditions: Adenoiditis
Adenotonsillar Hypertrophy
Obstructive Sleep Apnea
Tonsillitis

Interventions: Drug: Normal Saline
Drug: Dexmedetomidine

First Posted Date: 2014-06-12

Last Posted Date: 2020-04-09

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 92

Registration Number: NCT02162433

Locations: 🇺🇸
MEEI, Boston, Massachusetts, United States

Computer-Based Auditory Rehabilitation

Not Applicable

Completed

Conditions: Presbycusis

Interventions: Behavioral: Video game based training 2
Behavioral: Video game based training 1

First Posted Date: 2014-05-28

Last Posted Date: 2016-10-18

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 36

Registration Number: NCT02147847

Locations: 🇺🇸
Hudson Valley Audiology Center, New City, New York, United States
🇺🇸
Saint Elizabeth's Medical Center, Brighton, Massachusetts, United States
🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Prevalence of Dyschromatopsia in Glaucoma Patients

Withdrawn

Conditions: Open Angle Glaucoma

First Posted Date: 2013-11-26

Last Posted Date: 2013-11-26

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Registration Number: NCT01994564

Locations: 🇺🇸
Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, United States

In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions

Terminated

Conditions: Primary Acquired Melanosis
Nevus
Conjunctival Malignant Melanoma
Racial Melanosis

Interventions: Procedure: HRT III with Non-Contact Cornea Rostock Module

First Posted Date: 2013-11-25

Last Posted Date: 2016-08-15

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 17

Registration Number: NCT01993654

Locations: 🇺🇸
Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸
Wills Eye Hospital, Philadelphia, Pennsylvania, United States

Safety and Efficacy of Topical Tacrolimus 0.05% in the Treatment of Ocular Graft-Versus-Host Disease

Phase 1

Completed

Conditions: Ocular GVHD

Interventions: Drug: Methylprednisolone Sodium Succinate
Drug: Tacrolimus

First Posted Date: 2013-11-07

Last Posted Date: 2017-05-15

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 40

Registration Number: NCT01977781

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial

Phase 4

Completed

Conditions: Sinusitis

Interventions: Drug: Amoxicillin-Potassium Clavulanate
Drug: Placebo

First Posted Date: 2013-08-09

Last Posted Date: 2020-02-25

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 134

Registration Number: NCT01919411

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

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