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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study on The Effect of Hepatic Impairment on The Pharmacokinetics of RO4917838

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-05-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
35
Registration Number
NCT01356550

A Study of MIRCERA for the Intrapetient Variability of Hemoglobin Levels in Patients With Chronic Renal Anemia (RIVAL)

Completed
Conditions
Anemia
First Posted Date
2011-05-19
Last Posted Date
2017-07-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1288
Registration Number
NCT01356589
Locations
🇬🇷

Ahepa Hospital; 1St Dept. of Medicine, Thessaloniki, Greece

🇬🇷

Kyanous Stavros of Patras, Renal Disease Therapy Unit, Patra, Greece

🇬🇷

General Hospital Tzanio ; Nephrology, Piraeus, Greece

and more 30 locations

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-05-16
Last Posted Date
2014-06-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
39
Registration Number
NCT01353859

An Observational Study of Avastin (Bevacizumab) in Combination With Interferon Alpha-2a as First-Line Treatment in Patients With Advanced and/or Metastatic Renal Cell Carcinoma

Completed
Conditions
Renal Cell Cancer
First Posted Date
2011-05-11
Last Posted Date
2017-10-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5
Registration Number
NCT01351571

A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)

Phase 3
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2011-05-10
Last Posted Date
2017-09-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
485
Registration Number
NCT01351415
Locations
🇺🇸

University of Pennsylvania; Radiation Oncology, Philadelphia, Pennsylvania, United States

🇯🇵

Miyagi Cancer Center; Respiratory Medicine, Miyagi, Japan

🇺🇸

USA Mitchell Cancer Institute, Mobile, Alabama, United States

and more 176 locations

A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-05-02
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT01345942

A Study of Administration of Trastuzumab (Herceptin) by a Single-use Injection Device Versus a Handheld Syringe

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-04-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
119
Registration Number
NCT01344863

An Observational Study on The Prediction of Adverse Events in Patients With Chronic Hepatitis C Receiving a Long-Acting Interferon Plus Ribavirin (GUARD-C)

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2011-04-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
4459
Registration Number
NCT01344889

An Observational Study on Patients With Non-Squamous NSCLC Who Reached A Long PFS After Avastin (Bevacizumab)-Based First-Line Therapy

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2011-04-28
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
118
Registration Number
NCT01343914

An Observational Study on Bevacizumab (Avastin) as First-Line Treatment in Colorectal Cancer Participants With Potentially Resectable Liver Metastases

Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2011-04-28
Last Posted Date
2017-04-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
210
Registration Number
NCT01343901
Locations
🇫🇷

Fondation Bergonie; Gastro-Enterologie, Bordeaux, France

🇫🇷

Clinique De L Europe; Pmsi, Amiens, France

🇫🇷

Clinique Esquirol Saint Hilaire, Agen, France

and more 121 locations
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