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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of RO4995819 in Combination With Citalopram in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-06-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
32
Registration Number
NCT01367756

A Study on The Effect of Multiple Dose Carbamazepine on Single Dose Pharmacokinetics of RO4917838 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-06-03
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01365403

A Study of Bevacizumab Versus Placebo in Combination With Carboplatin/Paclitaxel in Participants With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Previous Chemotherapy

Phase 3
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2011-06-02
Last Posted Date
2018-02-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
276
Registration Number
NCT01364012
Locations
🇨🇳

Beijing Hospital of Ministry of Health; Hematology, Beijing, China

🇨🇳

General Hospital of Chinese PLA; Department of Hematology, Beijing, China

🇨🇳

Beijing Chest Hospital; Oncology Department, Beijing, China

and more 14 locations

A Study of Herceptin (Trastuzumab) in Combination With Whole Brain Radiotherapy in Patients With HER-2 Positive Breast Cancer

Phase 2
Terminated
Conditions
Breast Cancer
Interventions
First Posted Date
2011-06-02
Last Posted Date
2014-08-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3
Registration Number
NCT01363986

A Formulation Screening Study of Dalcetrapib and Atorvastatin in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-06-02
Last Posted Date
2019-12-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01363999

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-05-27
Last Posted Date
2017-08-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
110
Registration Number
NCT01362062
Locations
🇮🇳

Excel Center, Guwahati, India

🇮🇳

Sir Gangaram Hospital, New Delhi, Delhi, India

🇮🇳

Healing Touch City Clinic, Chandigarh, India

and more 4 locations

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

First Posted Date
2011-05-24
Last Posted Date
2025-01-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
4804
Registration Number
NCT01358877
Locations
🇺🇸

Texas Oncology - DFW, Dallas, Texas, United States

🇺🇸

The Mark H. Zangmeister Ctr; Mid Ohio Onc/Hem Inc., Columbus, Ohio, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

and more 552 locations

A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: RO5429083
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
65
Registration Number
NCT01358903

A Study of RO6807952 in Patients With Diabetes Mellitus Type 2

Phase 1
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT01358929

An Observational Study of Lung Cancer Related Symptoms and Disease Control Rate in Patients With Non-Small Cell Lung Cancer Receiving First-Line Platinum-Based Chemotherapy With or Without Avastin (Bevacizumab)

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
156
Registration Number
NCT01358942
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