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Roche Holding AG

Roche Holding AG logo
πŸ‡¨πŸ‡­Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of RoActemra/Actemra and, if Initially Inadequately Responded to RoActemra/Actemra, Followed by MabThera/Rituxan in Patients With Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-04-11
Last Posted Date
2015-09-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
519
Registration Number
NCT01332994

An Observational Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Metastatic or Recurrent Non-Squamous Non-Small Cell Lung Cancer

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2011-04-11
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
423
Registration Number
NCT01333007

A Study of Danoprevir/Ritonavir and Copegus With RO5024048 and/or Pegasys in Patients With Chronic Hepatitis C

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2011-04-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
381
Registration Number
NCT01331850

A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-04-08
Last Posted Date
2017-07-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3080
Registration Number
NCT01331837
Locations
πŸ‡ΊπŸ‡Έ

Emory Uni ; Division of Rheumatology, Atlanta, Georgia, United States

πŸ‡ΊπŸ‡Έ

Apex Medical Research, AMR, Inc., Chicago, Illinois, United States

πŸ‡ΊπŸ‡Έ

Columbus Arthritis Center, Columbus, Ohio, United States

and more 423 locations

A Study of First-line Maintenance Erlotinib Versus Erlotinib at Disease Progression in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC) Who Have Not Progressed Following Platinum-Based Chemotherapy

Phase 3
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
Drug: Placebo
Drug: Second-Line Chemotherapy
First Posted Date
2011-04-05
Last Posted Date
2016-10-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
643
Registration Number
NCT01328951

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Phase 2
Completed
Conditions
Myocardial Infarction
Interventions
Procedure: Percutaneous Coronary Intervention (PCI)
Drug: placebo
First Posted Date
2011-04-01
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
532
Registration Number
NCT01327183

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-03-31
Last Posted Date
2017-08-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT01326962
Locations
πŸ‡ΈπŸ‡¦

Heraa General Hospital; Rheumatology, Makkah, Saudi Arabia

πŸ‡ΈπŸ‡¦

King Abdulaziz University Hospital, Jeddah, Saudi Arabia

πŸ‡ΈπŸ‡¦

King Fahad Specialist Hospital; Oncology, Dammam, Saudi Arabia

and more 1 locations

A Study of RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With Metastatic Colorectal Cancer

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2011-03-30
Last Posted Date
2022-11-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
169
Registration Number
NCT01326000

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Phase 3
Completed
Conditions
Coronary Heart Disease
Interventions
Drug: placebo
First Posted Date
2011-03-25
Last Posted Date
2019-07-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
300
Registration Number
NCT01323153

An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer

Completed
Conditions
Colorectal Cancer
First Posted Date
2011-03-22
Last Posted Date
2016-09-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
609
Registration Number
NCT01319877
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