MedPath

Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis

Completed
Conditions
Kidney Disease, Chronic
First Posted Date
2011-03-18
Last Posted Date
2017-07-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
340
Registration Number
NCT01318512
Locations
🇨🇿

Nemocnice Novy Jicin; Dialyzacni Stredisko, Novy Jicin, Czechia

A Study of Tarceva (Erlotinib) as First Line Therapy in Participants With Non-Small Cell Lung Cancer Harbouring Epidermal Growth Factor Receptor (EGFR) Mutations

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2011-03-07
Last Posted Date
2018-09-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
208
Registration Number
NCT01310036
Locations
🇨🇳

Changhua Christian Hospital; Internal Medicine, Changhua, Taiwan

🇨🇳

Veterans General Hospital; Internal Medicine, Kaohsiung, Taiwan

🇨🇳

Chang Gung Medical Foundation - Linkou; Chest Dept, Taoyuan, Taiwan

and more 19 locations

Observational Study to Investigate the Long-term Effects of MIRCERA in Clinical Routine

Completed
Conditions
Anemia
First Posted Date
2011-03-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1083
Registration Number
NCT01309269

An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease in Pre-Dialysis or Dialysis

Completed
Conditions
Anemia, Kidney Disease, Chronic
First Posted Date
2011-03-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
250
Registration Number
NCT01309295

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Sero-Positive Rheumatoid Arthritis Who Are Non-Responders or Intolerant to a Single TNF-Inhibitor (PORTSMAB)

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2011-03-07
Last Posted Date
2016-08-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
9
Registration Number
NCT01309282

A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma

Phase 1
Completed
Conditions
Carcinoma, Hepatocellular
Interventions
First Posted Date
2011-03-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01308723

A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma

Phase 1
Completed
Conditions
Glioblastoma Multiforme
Interventions
Drug: RO5323441 + bevacizumab [Avastin]
First Posted Date
2011-03-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT01308684

A Study of Vemurafenib in Participants With Metastatic Melanoma

Phase 3
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2011-03-02
Last Posted Date
2017-12-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3219
Registration Number
NCT01307397
Locations
🇦🇱

University "Mother Theresa" Hospital Center; Oncology Department, Tirana, Albania

🇦🇷

Hospital Britanico; Oncologia, Buenos Aires, Argentina

🇦🇷

Fundación CIDEA, Buenos Aires, Argentina

and more 277 locations

Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.

Phase 2
Completed
Conditions
Spinal Muscular Atrophy Type II
Spinal Muscular Atrophy Type III Non Ambulant
Interventions
Drug: Placebo
First Posted Date
2011-02-24
Last Posted Date
2016-11-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
165
Registration Number
NCT01302600
Locations
🇫🇷

Hôpital Raymond Poincaré, Garches, France

🇫🇷

Hôpital Femme-Mère-Enfant, Bron, France

🇩🇪

University of Essen, Essen, Germany

and more 18 locations

A Study of Herceptin (Trastuzumab) in Combination With a Taxane in Participants With HER2-Positive Breast Cancer Who Relapsed After (Neo)Adjuvant Herceptin Treatment

Phase 4
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2011-02-23
Last Posted Date
2016-12-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
32
Registration Number
NCT01301729
© Copyright 2025. All Rights Reserved by MedPath