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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Observational Study on Predictors of Response to Invirase (Saquinavir) Treatment in Treatment-naïve Patients With HIV Infection

Completed
Conditions
HIV Infections
First Posted Date
2011-02-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
151
Registration Number
NCT01297127

A Study of the Safety of Individualized Combination Therapy With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C (MASTER)

Phase 3
Withdrawn
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2011-02-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT01296971

A Study of the Correlation Between Pharmacokinetic and Pharmacodynamic Parameters of CellCept (Mycophenolate Mofetil).

Phase 2
Completed
Conditions
Kidney Transplantation
Interventions
Drug: antibody induction
Drug: corticosteroid
First Posted Date
2011-02-09
Last Posted Date
2016-05-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT01292226

A Study to Compare Subcutaneous Versus Intravenous MabThera (Rituximab) in Combination With Chemotherapy in Patients With Chronic Lymphocytic Leukemia

Phase 1
Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2011-02-09
Last Posted Date
2018-12-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
240
Registration Number
NCT01292603
Locations
🇧🇷

Hospital das Clinicas - FMUSP, Sao Paulo, SP, Brazil

🇦🇷

HOSPITAL PRIVADO - CENTRO MEDICO DE CÓRDOBA; Dpto Oncología, Córdoba, Argentina

🇩🇪

Klinik der Uni zu Köln; Klinik für Innere Medizin, Köln, Germany

and more 81 locations

A Study of Bonviva/Boniva (Ibandronate) in Biphosphonate-Naïve Women With Post-Menopausal Osteoporosis

Phase 3
Completed
Conditions
Post Menopausal Osteoporosis
Interventions
First Posted Date
2011-02-04
Last Posted Date
2015-08-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
41
Registration Number
NCT01290094

A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)

First Posted Date
2011-02-01
Last Posted Date
2019-04-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1418
Registration Number
NCT01287741
Locations
🇨🇦

Humber River Hospital, Toronto, Ontario, Canada

🇺🇸

UCLA - School of Medicine; Division of Hematology/Oncology, Los Angeles, California, United States

🇵🇱

Uniwersyteckie Centrum Kliniczne; Klinika Hematologii i Transplantologii, Gdansk, Poland

and more 232 locations

A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Who Present EGFR Mutations

Phase 4
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2011-02-01
Last Posted Date
2015-06-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01287754

A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 Mutation

Phase 2
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2011-01-31
Last Posted Date
2016-09-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
51
Registration Number
NCT01286753

Safety Extension Study of TRO19622 in ALS

Phase 2
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2011-01-28
Last Posted Date
2016-11-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
271
Registration Number
NCT01285583
Locations
🇫🇷

CHRU de LILLE - Hôpital Roger Salengro - Centre SLA-MMN - Sce de Neurologie et Pathologie du Mouvement, Lille, France

🇫🇷

HCL Hôpital Neurologique et Neurochirurgical Pierre Wertheimer - Neurologie C et Laboratoire d'électromyographie - 59, boulevard Pinel, Bron Cedex, France

🇫🇷

Clinique du Motoneurone - Sce d'Explorations Neurologiques - Hôpital Gui de Chauliac, Montpellier, France

and more 12 locations
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