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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors

First Posted Date
2016-03-22
Last Posted Date
2021-07-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
243
Registration Number
NCT02715531
Locations
🇺🇸

Stanford Cancer Institute; Hematology, Palo Alto, California, United States

🇺🇸

Georgetown University Medical Center, Washington, District of Columbia, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

and more 27 locations

A Single-Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Gantenerumab Following Subcutaneous (SC) Administration in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2016-03-17
Last Posted Date
2019-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT02711423
Locations
🇺🇸

Bioclinica Research, Orlando, Florida, United States

Utility Study in Diffuse Large B-Cell Lymphoma (DLBCL)

Completed
Conditions
Diffuse Large B-Cell Lymphoma
First Posted Date
2016-03-15
Last Posted Date
2017-04-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
91
Registration Number
NCT02708732
Locations
🇬🇧

PH Associates - an OPen Health Company, Marlow, United Kingdom

A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
First Posted Date
2016-03-14
Last Posted Date
2016-05-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
123
Registration Number
NCT02707640

Multifactorial Approach Associated With Orlistat (Xenical) for 4 Years Weight Loss Maintenance in Obese Adults

Phase 4
Completed
Conditions
Obesity
Interventions
First Posted Date
2016-03-11
Last Posted Date
2016-04-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
50
Registration Number
NCT02706067

A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome

Phase 2
Completed
Conditions
Sjogren's Syndrome
Interventions
Drug: Placebo
First Posted Date
2016-03-08
Last Posted Date
2018-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
75
Registration Number
NCT02701985
Locations
🇺🇸

Shanahan Rheumatology & Immunology, PLLC, Raleigh, North Carolina, United States

🇺🇸

Wallace Rheumatic Study Center, Beverly Hills, California, United States

🇺🇸

Winthrop University Hospital, Mineola, New York, United States

and more 28 locations

The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of RO6889450 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2016-03-04
Last Posted Date
2017-11-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
164
Registration Number
NCT02699372
Locations
🇳🇱

PRA Health Sciences Early Development Services, Zuidlaren, Netherlands

Study to Examine Efficacy and Safety of Rituximab in Participants With Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2016-03-04
Last Posted Date
2016-10-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
130
Registration Number
NCT02699892

Evaluation of Long-Term Safety of Pirfenidone (Esbriet) in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
First Posted Date
2016-03-04
Last Posted Date
2017-04-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1009
Registration Number
NCT02699879
Locations
🇦🇹

Medizinische Universitat Innsbruck; Department of Internal Medicine, Pneumology Centre, Innsbruck, Austria

🇩🇰

Aarhus University Hospital; Lungemed afd. B, Aarhus, Denmark

🇦🇹

LKH Hohenems; Abteilung für Pulmologie, Hohenems, Austria

and more 103 locations

A Study of Faricimab (RO6867461) in Participants With Center-Involving Diabetic Macular Edema

Phase 2
Completed
Conditions
Diabetic Macular Edema
Interventions
First Posted Date
2016-03-04
Last Posted Date
2020-09-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
229
Registration Number
NCT02699450
Locations
🇺🇸

United Med Res Inst, Inglewood, California, United States

🇺🇸

Ophthalmic Clinical Trials San Diego, Oceanside, California, United States

🇺🇸

Southern CA Desert Retina Cons, Palm Desert, California, United States

and more 56 locations
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