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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Patients With Spinal Muscular Atrophy (SMA)

Phase 2
Completed
Conditions
Muscular Atrophy, Spinal
Interventions
First Posted Date
2015-12-11
Last Posted Date
2019-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
131
Registration Number
NCT02628743
Locations
🇫🇷

Hopital Femme Mere Enfant; Medecine Physique et Readaptation Pediatrique - L'ESCALE, Bron, France

🇫🇷

Hôpital Raymond Poincare; Serv. Neurologie et Réanimation pédiatriques - Centre réf. neuromusculaire, Garches, France

🇫🇷

Hopital Jeanne De Flandre; CIC pediatrique, Lille, France

and more 21 locations

A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)

Phase 1
Completed
Conditions
Solid Tumor
Cancer of Head and Neck
Breast Cancer
Interventions
First Posted Date
2015-12-10
Last Posted Date
2022-11-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
134
Registration Number
NCT02627274
Locations
🇺🇸

The Ohio State University, Columbus, Ohio, United States

🇺🇸

UCSD - Moores Cancer Center, La Jolla, California, United States

🇨🇦

Princess Margaret Cancer Center, Toronto, Ontario, Canada

and more 23 locations

Bevacizumab in Metastatic Renal Cancer

Completed
Conditions
Renal Cell Cancer
Interventions
First Posted Date
2015-12-10
Last Posted Date
2016-08-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
365
Registration Number
NCT02627144

Health Care Personnel Time for Anemia Management With Erythropoiesis Stimulating Agents in Hemodialysis Centers in Croatia

Completed
Conditions
Renal Anemia of Chronic Kidney Disease
Interventions
Other: No intervention
First Posted Date
2015-12-09
Last Posted Date
2016-03-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
110
Registration Number
NCT02625844

A Study of Idasanutlin in Combination With Obinutuzumab in Relapsed/Refractory (R/R) Follicular Lymphoma (FL) and in Combination With Rituximab in R/R Diffuse Large B-Cell Lymphoma (DLBCL) Participants

Phase 1
Terminated
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2015-12-09
Last Posted Date
2020-05-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
25
Registration Number
NCT02624986
Locations
🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇩🇪

Charité Research Organisation GmbH Campus-Virchow-Klinikum, Berlin, Germany

🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

and more 21 locations

A Study of Recormon (Epoetin Beta) in Anemic Patients With Non-Myeloid Malignancy

Phase 4
Terminated
Conditions
Anemia
Interventions
First Posted Date
2015-12-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
10
Registration Number
NCT02624141

A Study on Rheumatoid Arthritis Patients Treated With Rituximab

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2015-12-04
Last Posted Date
2016-12-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
81
Registration Number
NCT02622503

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Phase 1
Completed
Conditions
Glaucoma
Interventions
First Posted Date
2015-12-04
Last Posted Date
2018-03-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT02622334
Locations
🇺🇸

Cornerstone Eye Care, Div of Cornerstone Health Care, High Point, North Carolina, United States

🇸🇬

Singapore National Eye Centre; Glaucoma Department, Singapore, Singapore

🇺🇸

New York Eye and Ear Infirmary of Mt. Sinai; New York Glaucoma Research Institute, New York, New York, United States

and more 4 locations

Clinical Progression of Mild to Moderate Idiopathic Pulmonary Fibrosis (IPF) Under a Therapy With Esbriet® (Pirfenidone)

Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
First Posted Date
2015-12-04
Last Posted Date
2017-02-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT02622477
Locations
🇩🇪

Praxis Dr. med. Wilhelm Ammenwerth, Bochum, Germany

🇩🇪

Universitätsklinikum Freiburg, Abteilung Pneumologie, Freiburg, Germany

🇩🇪

Kliniken der Stadt Köln gGmbH Krankenhaus Merheim, Köln, Germany

and more 14 locations

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors

Phase 3
Completed
Conditions
Hemophilia A
Interventions
First Posted Date
2015-12-04
Last Posted Date
2021-06-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
113
Registration Number
NCT02622321
Locations
🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Boston Childrens Hospital, Boston, Massachusetts, United States

🇯🇵

Hospital of the University of Occupational and Environmental Health,Japan, Kitakyushu-shi, Japan

and more 41 locations
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