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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2015-12-03
Last Posted Date
2018-08-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT02621047
Locations
🇸🇰

Summit Clinical Research s.r.o.; Oddelenie internej mediciny a klinickej farmakologie, Bratislava, Slovakia

🇨🇿

Pharmaceutical Research Associates CZ, s.r.o., Praha 7, Czechia

A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)

Phase 1
Completed
Conditions
End Stage Renal Disease
Interventions
First Posted Date
2015-12-01
Last Posted Date
2016-02-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT02617784

A Study To Observe Treatment Patterns and Outcomes in Patients With HER2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer

Withdrawn
Conditions
Breast Cancer, HER2 Positive Breast Cancer, Metastatic Breast Cancer, Locally Advanced Breast Cancer
Interventions
Other: No intervention
First Posted Date
2015-11-26
Last Posted Date
2017-02-23
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT02616224

A Study of the Efficacy and Safety of Tocilizumab for Confirmed Rheumatoid Arthritis (RA) Participants in Clinical Practice

Terminated
Conditions
Rheumatoid Arthritis
Interventions
Other: No intervention
First Posted Date
2015-11-26
Last Posted Date
2018-10-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT02616328
Locations
🇸🇦

King Khaled Uni Hospital; Oncology, Riyadh, Saudi Arabia

🇸🇦

King Fahad Medical City; Gastroentrology, Riyadh, Saudi Arabia

A Study to Develop Predictive and Prognostic Tools for Optimizing Therapy With Bevacizumab Frontline Cancer Therapy in Participants With HER 2-Negative Aggressive Metastatic Breast Cancer

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2015-11-24
Last Posted Date
2020-02-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
111
Registration Number
NCT02613208
Locations
🇪🇸

Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon, Spain

🇪🇸

Hospital Universitario Son Espases; Servicio de Oncologia, Palma De Mallorca, Islas Baleares, Spain

🇪🇸

Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, La Coruna, LA Coruña, Spain

and more 22 locations

Observation of Patients With Metastatic Colorectal Cancer Starting Chemotherapy Combined With Bevacizumab (Avastin)

Completed
Conditions
Metastatic Colorectal Cancer
Interventions
Other: Observational Chemotherapy
First Posted Date
2015-11-23
Last Posted Date
2016-03-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
765
Registration Number
NCT02612077

Accu-Chek® CONNECT at School (CATS) Pediatric Study

Not Applicable
Completed
Conditions
Diabetes Mellitus, Type 1
Interventions
Device: DMS
Device: Accu-Chek® CONNECT DMS
First Posted Date
2015-11-20
Last Posted Date
2018-05-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
196
Registration Number
NCT02609633
Locations
🇺🇸

Pediatric Endocrinology of Phoenix, Phoenix, Arizona, United States

🇺🇸

Barbara Davis Center for Childhood Diabetes, Aurora, Colorado, United States

🇺🇸

Nemours Childrens Hospital, Pensacola, Florida, United States

and more 10 locations

A Study of Obinutuzumab, Rituximab, Polatuzumab Vedotin, and Venetoclax in Relapsed or Refractory Follicular Lymphoma (FL) or Diffuse Large B-Cell Lymphoma (DLBCL)

Phase 1
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2015-11-20
Last Posted Date
2023-10-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
133
Registration Number
NCT02611323
Locations
🇮🇹

Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori, Meldola, Emilia-Romagna, Italy

🇮🇹

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia, Italy

🇮🇹

SCDU Ematologia, Novara, Piemonte, Italy

and more 20 locations

A Study to Observe Treatment Patterns and Outcomes in Participants in Saudi Arabia With Human Epidermal Growth Factor Receptor 2 (HER2-Positive) Unresectable Locally Advanced or Metastatic Breast Cancer (LA/mBC)

Terminated
Conditions
Metastatic Breast Cancer
Interventions
Other: No intervention
First Posted Date
2015-11-20
Last Posted Date
2020-01-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
15
Registration Number
NCT02611310
Locations
🇸🇦

National Guard King Abdulaziz Medical City; Oncology, Riyadh, Saudi Arabia

🇸🇦

King Abdullah Medical City-Holy Makkah, Holy Makkah, Saudi Arabia

🇸🇦

King Fahad Medical City; Gastroentrology, Riyadh, Saudi Arabia

A Study of Capecitabine (Xeloda) as First-Line Chemotherapy in Participants With Metastatic Nasopharyngeal Cancer

Phase 2
Completed
Conditions
Nasopharyngeal Cancer
Interventions
First Posted Date
2015-11-18
Last Posted Date
2016-03-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT02608073
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