GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

First Posted Date
2016-06-09
Last Posted Date
2024-12-05
Lead Sponsor
Genentech, Inc.
Target Recruit Count
518
Registration Number
NCT02794571
Locations
🇰🇷

Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of

🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

🇺🇸

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

and more 25 locations

A Safety Study of Intravenously Administered UTTR1147A in Healthy Volunteers (HVs), Participants With Ulcerative Colitis (UC), and Participants With Crohn's Disease (CD)

First Posted Date
2016-04-25
Last Posted Date
2020-10-30
Lead Sponsor
Genentech, Inc.
Target Recruit Count
70
Registration Number
NCT02749630
Locations
🇬🇧

Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom

🇩🇪

Charité Research Organisation GmbH, Berlin, Germany

A Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of BITS7201A in Healthy Volunteers and Participants With Mild Atopic Asthma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-04-22
Last Posted Date
2018-07-03
Lead Sponsor
Genentech, Inc.
Target Recruit Count
67
Registration Number
NCT02748642
Locations
🇺🇸

New Orleans Center for Clinical Research; Volunteer Research Group, Knoxville, Tennessee, United States

A Study to Determine the Safety, Tolerability, and Pharmacokinetics of GDC-0310 in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-04-19
Last Posted Date
2020-02-20
Lead Sponsor
Genentech, Inc.
Target Recruit Count
95
Registration Number
NCT02742779
Locations
🇺🇸

PRA Health Sciences, Salt Lake City, Utah, United States

Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810

First Posted Date
2016-03-29
Last Posted Date
2017-08-22
Lead Sponsor
Genentech, Inc.
Target Recruit Count
45
Registration Number
NCT02722018
Locations
🇬🇧

Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects

First Posted Date
2016-03-04
Last Posted Date
2020-03-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
50
Registration Number
NCT02699710
Locations
🇬🇧

Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

A Study in Patients With Neovascular Age Related Macular Degeneration or Macular Edema Secondary To Retinal Vein Occlusion to Evaluate Usability of the Ranibizumab (Lucentis®) Prefilled Syringe (PFS)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2016-03-03
Last Posted Date
2017-09-21
Lead Sponsor
Genentech, Inc.
Target Recruit Count
35
Registration Number
NCT02698566
Locations
🇺🇸

Southeastern Retina Associates, Chattanooga, Tennessee, United States

🇺🇸

Char Eye Ear &Throat Assoc, Charlotte, North Carolina, United States

🇺🇸

Paducah Retinal Center, Paducah, Kentucky, United States

and more 1 locations

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

First Posted Date
2016-02-23
Last Posted Date
2024-06-04
Lead Sponsor
Genentech, Inc.
Target Recruit Count
131
Registration Number
NCT02688985
Locations
🇺🇸

Ohio State University, Columbus, Ohio, United States

🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

University of Massachusetts Medical School, Worcester, Massachusetts, United States

and more 14 locations

A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

First Posted Date
2016-01-14
Last Posted Date
2020-08-06
Lead Sponsor
Genentech, Inc.
Target Recruit Count
54
Registration Number
NCT02655614
Locations
🇺🇸

Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

🇺🇸

Mayo Clinic Hospital - Florida, Jacksonville, Florida, United States

🇺🇸

Forbes Norris Mda/als Ctr; Research Center, San Francisco, California, United States

and more 7 locations

Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-12-28
Last Posted Date
2019-12-23
Lead Sponsor
Genentech, Inc.
Target Recruit Count
72
Registration Number
NCT02640092
Locations
🇺🇸

Molecular NeuroImaging, New Haven, Connecticut, United States

🇺🇸

Bio Behavioral Health, Toms River, New Jersey, United States

🇺🇸

NeuroCognitive Institute, Mount Arlington, New Jersey, United States

and more 13 locations
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