Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated logo
🇺🇸United States
Ownership
Public
Established
1989-01-01
Employees
5.4K
Market Cap
$123.9B
Website
http://www.vrtx.com

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have the R117H-CF Transmembrane Conductance Regulator (CFTR) Mutation (KONDUCT)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-06-08
Last Posted Date
2015-02-12
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
70
Registration Number
NCT01614457

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have a Non-G551D CF Transmembrane Conductance Regulator (CFTR) Gating Mutation

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-06-08
Last Posted Date
2014-10-29
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
39
Registration Number
NCT01614470

24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate

First Posted Date
2012-05-03
Last Posted Date
2015-11-20
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
359
Registration Number
NCT01590459
Locations
🇺🇦

Vertex Investigational Site, Vinnytsia, Ukraine

VX-222 + Telaprevir + Ribavirin for 12 or 16 Weeks in Treatment-Naive Subjects With Genotype 1a Hepatitis C

First Posted Date
2012-04-20
Last Posted Date
2014-07-04
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
64
Registration Number
NCT01581138

A Study to Investigate VX-787 Given to Adult Volunteers Inoculated With Live Influenza Virus

Phase 2
Completed
Conditions
Interventions
First Posted Date
2012-03-23
Last Posted Date
2016-09-02
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
140
Registration Number
NCT01561807

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

First Posted Date
2012-02-13
Last Posted Date
2018-04-13
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
194
Registration Number
NCT01531673
Locations
🇬🇧

Vertex Investigational Site, Cardiff, Vale Of Glamorgen, United Kingdom

A Study to Assess the Relative Bioavailability Three New Formulations of Telaprevir in Healthy Subjects

First Posted Date
2012-01-18
Last Posted Date
2012-07-04
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
64
Registration Number
NCT01511432
Locations
🇺🇸

Texas, Dallas, Texas, United States

🇺🇸

Wisconsin, Madison, Wisconsin, United States

A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial Epilepsy

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2011-12-29
Last Posted Date
2020-09-30
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
55
Registration Number
NCT01501383
Locations
🇺🇸

Idaho, Boise, Idaho, United States

🇺🇸

Virginia, Charlottesville, Virginia, United States

🇩🇪

Germany, Kork, Germany

and more 17 locations

Telaprevir, Peg-IFN-alfa-2a, and RBV in Treatment-Experienced Black/African American and Non-Black/African American Subjects With Genotype 1 Chronic Hepatitis C

First Posted Date
2011-11-08
Last Posted Date
2015-08-03
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
121
Registration Number
NCT01467492
Locations
🇺🇸

Georgia, Atlanta, Georgia, United States

🇺🇸

Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

Washington, DC, Washington, District of Columbia, United States

and more 15 locations
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