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Arcus Biosciences

Arcus Biosciences logo
๐Ÿ‡บ๐Ÿ‡ธUnited States
Ownership
Public
Established
2015-01-01
Employees
577
Market Cap
-
Website
http://www.arcusbio.com
Introduction

Arcus Biosciences, Inc. engages in the development and commercialization of immunotherapies. It competes in the segments of the pharmaceutical, biotechnology and other related markets that develop immunotherapies for the treatment of cancer. The company was founded by Terry J. Rosen and Juan Carlos Jaen in 2015 and is headquartered in Hayward, CA.

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Phase 2
Active, not recruiting
Conditions
Gastrointestinal Tract Malignancies
Interventions
First Posted Date
2022-04-15
Last Posted Date
2025-06-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
332
Registration Number
NCT05329766
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic - Arizona, Phoenix, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ronald Reagan UCLA Medical Center, Santa Monica, California, United States

and more 46 locations

A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-03-14
Last Posted Date
2024-05-24
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
24
Registration Number
NCT05277012
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Investigational Site, Lincoln, Nebraska, United States

A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2021-12-10
Last Posted Date
2024-05-24
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
20
Registration Number
NCT05154136
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Celerion, Lincoln, Nebraska, United States

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2021-11-11
Last Posted Date
2024-10-17
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
70
Registration Number
NCT05117554
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

Investigational Site, Groningen, Netherlands

A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies

Phase 1
Active, not recruiting
Conditions
Melanoma
Advanced Solid Tumor
Esophageal Cancer
Non Small Cell Lung Cancer (NSCLC)
Multiple Myeloma
Cervical Cancer
Lymphoma, Non-Hodgkin
Diffuse Large B Cell Lymphoma (DLBCL)
Gastroesophageal Junction Adenocarcinoma
Gastric Cancer
Interventions
First Posted Date
2021-02-26
Last Posted Date
2025-06-29
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
94
Registration Number
NCT04772989
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UCLA Department of Medicine - Hematology/Oncology, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic Jacksonville - PPDS, Jacksonville, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Goshen Health System, Goshen, Indiana, United States

and more 19 locations

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Phase 2
Active, not recruiting
Conditions
Squamous Non Small Cell Lung Cancer
Non Small Cell Lung Cancer
Nonsquamous Non Small Cell Lung Cancer
Lung Cancer
Interventions
First Posted Date
2021-02-03
Last Posted Date
2025-03-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
169
Registration Number
NCT04736173
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Hope and Healing Cancer Service, Hinsdale, Illinois, United States

๐Ÿ‡ฌ๐Ÿ‡ท

General hospital of Athens, chest diseases Sotiria, Athens, Greece

๐Ÿ‡ฌ๐Ÿ‡ท

University General Hospital "Attikon", Chaidari, Greece

and more 88 locations

An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.

Phase 1
Active, not recruiting
Conditions
Metastatic Colorectal Cancer
Interventions
First Posted Date
2020-12-09
Last Posted Date
2025-06-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
227
Registration Number
NCT04660812
Locations
๐Ÿ‡ช๐Ÿ‡ธ

Corporacio Sanitaria Parc Tauli, Sabadell, Spain

๐Ÿ‡บ๐Ÿ‡ธ

Arizona Clinical Research Center Inc, Tucson, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

City of Hope Comprehensive Cancer Center, Duarte, California, United States

and more 41 locations

A Study to Investigate the Pharmacokinetic Profile of Oral AB680 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Other: Placebo
First Posted Date
2020-10-05
Last Posted Date
2024-05-24
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
32
Registration Number
NCT04575311
Locations
๐Ÿ‡ฆ๐Ÿ‡บ

Nucleus Network, Melbourne, Victoria, Australia

Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

Phase 1
Active, not recruiting
Conditions
Androgen-Resistant Prostatic Neoplasms
Castration Resistant Prostatic Neoplasms
Prostatic Neoplasms, Castration-Resistant
Prostatic Cancer, Castration-Resistant
Interventions
First Posted Date
2020-05-11
Last Posted Date
2024-06-03
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
173
Registration Number
NCT04381832
Locations
๐Ÿ‡บ๐Ÿ‡ธ

The Oncology Institute of Hope & Innovation, Cerritos, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

The University of California, Los Angeles, Encino, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

The University of California, Irvine Medical Center, Orange, California, United States

and more 16 locations

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Phase 2
Active, not recruiting
Conditions
Squamous Non Small Cell Lung Cancer
Non Small Cell Lung Cancer
Lung Cancer
Nonsquamous Non Small Cell Lung Cancer
Interventions
First Posted Date
2020-02-10
Last Posted Date
2025-06-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
151
Registration Number
NCT04262856
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Alabama at Birmingham, Birmingham, Alabama, United States

๐Ÿ‡บ๐Ÿ‡ธ

Innovative Clinical Research Institute (ICRI), Whittier, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Florida Cancer Specialists, Gainesville, Florida, United States

and more 40 locations
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