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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Phase 3
Not yet recruiting
Conditions
Bipolar Disorder Type I With Mania
Interventions
First Posted Date
2025-04-16
Last Posted Date
2025-06-25
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
300
Registration Number
NCT06929273
Locations
🇺🇸

Local Institution - 0120, Glendale, Arizona, United States

🇺🇸

Local Institution - 0022, Bentonville, Arkansas, United States

🇺🇸

Local Institution - 0021, Little Rock, Arkansas, United States

and more 120 locations

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Phase 2
Not yet recruiting
Conditions
Breast Neoplasms
Interventions
First Posted Date
2025-04-15
Last Posted Date
2025-06-25
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
560
Registration Number
NCT06926868
Locations
🇺🇸

Local Institution - 0303, Hot Springs, Arkansas, United States

🇺🇸

Local Institution - 0307, Cerritos, California, United States

🇺🇸

Local Institution - 0308, Cerritos, California, United States

and more 218 locations

A Study to Investigate the Safety, Tolerability, and Drug Levels of BMS-986419 (Part 1) and the Effects Multiple Doses of BMS-986419 on Cardiac Repolarization (Part 2) in Healthy Participants

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
Drug: BMS-986419 Matching Placebo
Drug: Moxifloxacin Matching Placebo
First Posted Date
2025-03-25
Last Posted Date
2025-04-01
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
74
Registration Number
NCT06846866
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With Schizophrenia

Phase 3
Recruiting
Conditions
Schizophrenia
Interventions
Other: Placebo
First Posted Date
2025-03-19
Last Posted Date
2025-06-20
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
250
Registration Number
NCT06882785
Locations
🇯🇵

Local Institution - 0034, Konan, Aichi, Japan

🇯🇵

Okehazama Hospital, Toyoake, Aichi, Japan

🇯🇵

Local Institution - 0003, Toyoake, Aichi, Japan

and more 47 locations

A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132

Phase 4
Not yet recruiting
Conditions
Systemic Lupus Erythematosus (SLE)
Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
Interventions
First Posted Date
2025-03-14
Last Posted Date
2025-03-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
35
Registration Number
NCT06875960
Locations
🇺🇸

Local Institution - 0001, Farmington, Connecticut, United States

🇺🇸

Local Institution - 0002, New York, New York, United States

🇺🇸

Local Institution - 0003, Jackson, Tennessee, United States

A Single-dose Study to Evaluate the Safety, Tolerability, Drug Levels, and Relative Biological Availability of Alternate Formulations of BMS-986460 in Healthy Adult Male Participants

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
First Posted Date
2025-03-14
Last Posted Date
2025-05-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
56
Registration Number
NCT06877702
Locations
🇺🇸

ICON Lenexa, Lenexa, Kansas, United States

🇺🇸

Local Institution - 0002, Lenexa, Kansas, United States

A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis

Phase 3
Recruiting
Conditions
Juvenile Psoriatic Arthritis
Interventions
Other: Placebo
First Posted Date
2025-03-11
Last Posted Date
2025-06-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
60
Registration Number
NCT06869551
Locations
🇺🇸

Local Institution - 0038, Lancaster, California, United States

🇺🇸

Local Institution - 0020, Chicago, Illinois, United States

🇺🇸

Local Institution - 0023, Indianapolis, Indiana, United States

and more 39 locations

A Study of BMS-986504 in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion

Phase 2
Recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2025-03-04
Last Posted Date
2025-05-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
130
Registration Number
NCT06855771
Locations
🇺🇸

Local Institution - 0088, Anchorage, Alaska, United States

🇺🇸

Local Institution - 0099, Boise, Idaho, United States

🇺🇸

Local Institution - 0090, Boston, Massachusetts, United States

and more 67 locations

A Study to Evaluate Luspatercept Treatment Patterns and Outcomes in Erythropoiesis-Stimulating Agents-Naïve Patients With Lower-Risk Myelodysplastic Syndromes in the United States

Active, not recruiting
Conditions
Myelodysplastic Syndromes
Interventions
Drug: Erythropoiesis-stimulating agents
First Posted Date
2025-02-28
Last Posted Date
2025-02-28
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
400
Registration Number
NCT06851065
Locations
🇺🇸

RTI Health Solutions, Raleigh, North Carolina, United States

Safety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric Disorders

Phase 1
Recruiting
Conditions
Psychiatric Disorders
Interventions
First Posted Date
2025-02-28
Last Posted Date
2025-05-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
36
Registration Number
NCT06853171
Locations
🇺🇸

Pillar Clinical Research- Little Rock, Little Rock, Arkansas, United States

🇺🇸

NRC Research Institute, Orange, California, United States

🇺🇸

CenExel iResearch, LLC, Decatur, Georgia, United States

and more 1 locations
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