Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant

Phase 3

Completed

Conditions: Malignant Neoplasm

Interventions: Procedure: Psychosocial Assessment and Care
Procedure: Music Therapy
Other: Quality-of-Life Assessment

First Posted Date: 2006-03-22

Last Posted Date: 2022-07-15

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 118

Registration Number: NCT00305851

Locations: 🇺🇸
Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States
🇺🇸
Children's Oncology Group, Philadelphia, Pennsylvania, United States

Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor

Phase 3

Completed

Conditions: Stage III Adrenal Cortical Carcinoma AJCC v7
Stage I Adrenal Cortical Carcinoma AJCC v7
Stage II Adrenal Cortical Carcinoma AJCC v7
Stage IV Adrenal Cortical Carcinoma AJCC v7

Interventions: Procedure: Conventional Surgery
Drug: Cisplatin
Drug: Doxorubicin Hydrochloride
Drug: Etoposide
Biological: Filgrastim
Drug: Mitotane
Biological: Pegfilgrastim

First Posted Date: 2006-03-17

Last Posted Date: 2024-02-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 78

Registration Number: NCT00304070

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Banner University Medical Center - Tucson, Tucson, Arizona, United States

and more 88 locations

Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma

Phase 3

Completed

Conditions: Childhood Favorable Prognosis Hodgkin Lymphoma
Childhood Lymphocyte Depletion Hodgkin Lymphoma
Childhood Mixed Cellularity Hodgkin Lymphoma
Childhood Nodular Sclerosis Hodgkin Lymphoma
Stage I Childhood Hodgkin Lymphoma
Stage II Childhood Hodgkin Lymphoma

Interventions: Radiation: radiation therapy
Drug: doxorubicin hydrochloride
Drug: vincristine sulfate
Drug: prednisone
Drug: cyclophosphamide
Drug: ifosfamide
Drug: vinorelbine tartrate
Drug: dexamethasone
Drug: etoposide phosphate
Drug: cisplatin
Drug: cytarabine
Biological: filgrastim

First Posted Date: 2006-03-13

Last Posted Date: 2021-03-30

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 287

Registration Number: NCT00302003

Locations: 🇺🇸
Children's Oncology Group, Arcadia, California, United States

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

Phase 3

Completed

Conditions: Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7
Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Stage II Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7
Stage I Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7
Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

Interventions: Drug: Amifostine
Other: Laboratory Biomarker Analysis
Drug: Cisplatin
Radiation: Radiation Therapy
Drug: Fluorouracil

First Posted Date: 2006-01-11

Last Posted Date: 2022-10-25

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 111

Registration Number: NCT00274937

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Banner University Medical Center - Tucson, Tucson, Arizona, United States

and more 106 locations

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

Completed

Conditions: Childhood Acute Lymphoblastic Leukemia in Remission

Interventions: Behavioral: Compliance Monitoring
Other: Laboratory Biomarker Analysis
Drug: Mercaptopurine
Drug: Methotrexate
Other: Questionnaire Administration
Other: Study of Socioeconomic and Demographic Variables

First Posted Date: 2005-12-22

Last Posted Date: 2020-07-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 720

Registration Number: NCT00268528

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 132 locations

Radiation Therapy in Treating Young Patients With Gliomas

Phase 2

Completed

Conditions: Brain Tumor
Central Nervous System Tumor

Interventions: Radiation: radiation therapy

First Posted Date: 2005-10-13

Last Posted Date: 2019-08-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 92

Registration Number: NCT00238264

Locations: 🇺🇸
UAB Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 142 locations

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Phase 1

Completed

Conditions: Brain and Central Nervous System Tumors
Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Drug: irinotecan hydrochloride
Drug: temozolomide
Drug: vincristine sulfate

First Posted Date: 2005-08-30

Last Posted Date: 2023-10-02

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 42

Registration Number: NCT00138216

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Children's Hospital of Orange County, Orange, California, United States
🇺🇸
Stanford Cancer Center, Stanford, California, United States

and more 15 locations

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma

Phase 3

Completed

Conditions: Localized Osteosarcoma
Metastatic Osteosarcoma

Interventions: Drug: Cisplatin
Drug: Doxorubicin Hydrochloride
Drug: Methotrexate
Drug: Etoposide
Other: Quality-of-Life Assessment
Biological: Peginterferon Alfa-2b
Drug: Ifosfamide
Other: Questionnaire Administration
Procedure: Therapeutic Conventional Surgery

First Posted Date: 2005-08-24

Last Posted Date: 2023-06-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 1334

Registration Number: NCT00134030

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Phoenix Childrens Hospital, Phoenix, Arizona, United States

and more 215 locations

Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma

Phase 1

Terminated

Conditions: Central Nervous System Tumors
Brain Tumors

Interventions: Biological: filgrastim
Drug: topotecan hydrochloride
Radiation: radiation therapy

First Posted Date: 2005-04-06

Last Posted Date: 2013-12-10

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 7

Registration Number: NCT00107471

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama-Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 77 locations

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Phase 1

Completed

Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Brain and Central Nervous System Tumors

Interventions: Drug: valproic acid

First Posted Date: 2005-04-06

Last Posted Date: 2014-08-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 26

Registration Number: NCT00107458

Locations: 🇺🇸
Children's Hospital of Orange County, Orange, California, United States
🇺🇸
Stanford Comprehensive Cancer Center - Stanford, Stanford, California, United States
🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States

and more 14 locations

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Children's Oncology Group

Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant

Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor

Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

Radiation Therapy in Treating Young Patients With Gliomas

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma

Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors