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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Phase 3

Completed

Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Cardiac Toxicity

Interventions: Drug: enalapril maleate
Procedure: quality-of-life assessment

First Posted Date: 2004-03-01

Last Posted Date: 2014-08-05

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 13

Registration Number: NCT00003070

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 58 locations

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

Phase 2

Completed

Conditions: Brain Tumors
Central Nervous System Tumors

Interventions: Biological: filgrastim
Drug: cisplatin
Drug: cyclophosphamide
Drug: etoposide
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2004-02-20

Last Posted Date: 2014-07-25

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 53

Registration Number: NCT00003573

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States

and more 103 locations

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Phase 1

Completed

Conditions: Central Nervous System Tumors
Brain Tumors

Interventions: Drug: etoposide
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2004-02-20

Last Posted Date: 2014-07-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 31

Registration Number: NCT00003935

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States

and more 107 locations

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Not Applicable

Completed

Conditions: Brain Tumor
Central Nervous System Tumor

Interventions: Drug: carboplatin
Drug: temozolomide
Drug: vincristine sulfate

First Posted Date: 2004-02-11

Last Posted Date: 2018-05-16

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 66

Registration Number: NCT00077207

Locations: 🇺🇸
Childrens Oncology Group, Philadelphia, Pennsylvania, United States

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Phase 3

Completed

Conditions: Cardiac Toxicity
Sarcoma

Interventions: Drug: cisplatin
Drug: dexrazoxane hydrochloride
Drug: doxorubicin hydrochloride
Drug: methotrexate
Drug: ifosfamide
Drug: etoposide
Procedure: conventional surgery

First Posted Date: 2004-02-09

Last Posted Date: 2014-08-05

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 253

Registration Number: NCT00003937

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States

and more 145 locations

Quality of Life in Children Treated for Cancer

Completed

Conditions: Leukemia
Lymphoma
Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Other: Quality of Life Forms

First Posted Date: 2004-02-02

Last Posted Date: 2013-08-23

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 538

Registration Number: NCT00005881

Locations: 🇺🇸
Cancer Center and Beckman Research Institute, City of Hope, Duarte, California, United States
🇺🇸
CCOP - Bay Area Tumor Institute, Oakland, California, United States
🇺🇸
CCOP - Colorado Cancer Research Program, Inc., Denver, Colorado, United States

and more 14 locations

Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Phase 3

Completed

Conditions: Acute Lymphoblastic Leukemia
Adult B Acute Lymphoblastic Leukemia
Childhood B Acute Lymphoblastic Leukemia

Interventions: Drug: Cyclophosphamide
Drug: Cytarabine
Drug: Daunorubicin Hydrochloride
Drug: Dexamethasone
Drug: Doxorubicin Hydrochloride
Drug: Leucovorin Calcium
Drug: Mercaptopurine
Drug: Methotrexate
Drug: Pegaspargase
Radiation: Radiation Therapy
Drug: Prednisone
Drug: Thioguanine
Drug: Vincristine Sulfate

First Posted Date: 2004-01-13

Last Posted Date: 2021-04-27

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 3154

Registration Number: NCT00075725

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
USA Health Strada Patient Care Center, Mobile, Alabama, United States

and more 231 locations

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Phase 3

Completed

Conditions: Adult Rhabdomyosarcoma
Embryonal Childhood Rhabdomyosarcoma
Embryonal-botryoid Childhood Rhabdomyosarcoma
Previously Untreated Childhood Rhabdomyosarcoma

Interventions: Procedure: conventional surgery
Drug: dactinomycin
Drug: vincristine sulfate
Drug: cyclophosphamide
Radiation: radiation therapy

First Posted Date: 2004-01-12

Last Posted Date: 2021-11-19

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 390

Registration Number: NCT00075582

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Childrens Hospital, Phoenix, Arizona, United States
🇺🇸
University of Arizona Health Sciences Center, Tucson, Arizona, United States

and more 160 locations

Interleukin-2 in Treating Children Who Have Undergone Bone Marrow Transplantation for Acute Myeloid Leukemia

Phase 1

Completed

Conditions: Leukemia

Interventions: Biological: aldesleukin

First Posted Date: 2003-12-31

Last Posted Date: 2013-06-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 1

Registration Number: NCT00009698

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States

and more 116 locations

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Phase 2

Completed

Conditions: Childhood Germ Cell Tumor
Drug/Agent Toxicity by Tissue/Organ
Extragonadal Germ Cell Tumor
Ovarian Cancer

First Posted Date: 2003-12-10

Last Posted Date: 2013-07-04

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 27

Registration Number: NCT00003811

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States

and more 107 locations

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