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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor

Phase 3

Completed

Conditions: Central Nervous System Tumor
Brain Tumor

Interventions: Biological: filgrastim
Drug: carboplatin
Drug: cisplatin
Drug: cyclophosphamide
Drug: etoposide
Radiation: radiation therapy

First Posted Date: 2004-06-11

Last Posted Date: 2018-09-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 24

Registration Number: NCT00085098

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 103 locations

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Phase 3

Completed

Conditions: Cardiac Toxicity
Lymphoma

Interventions: Biological: bleomycin sulfate
Biological: filgrastim
Drug: dexrazoxane hydrochloride
Drug: doxorubicin hydrochloride
Drug: etoposide
Drug: vincristine sulfate
Radiation: low-LET cobalt-60 gamma ray therapy
Radiation: low-LET electron therapy
Radiation: low-LET photon therapy

First Posted Date: 2004-05-26

Last Posted Date: 2013-08-26

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 294

Registration Number: NCT00002827

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 36 locations

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Phase 3

Completed

Conditions: Lymphoma
Cardiac Toxicity

Interventions: Biological: bleomycin sulfate
Biological: filgrastim
Drug: cyclophosphamide
Drug: dexrazoxane hydrochloride
Drug: doxorubicin hydrochloride
Drug: etoposide
Drug: prednisone
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2004-05-26

Last Posted Date: 2014-07-24

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 219

Registration Number: NCT00005578

Locations: 🇺🇸
University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
MBCCOP - University of South Alabama, Mobile, Alabama, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 60 locations

Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors

Phase 2

Completed

Conditions: Neuroblastoma
Brain and Central Nervous System Tumors

Interventions: Biological: filgrastim
Drug: carboplatin
Drug: cyclophosphamide
Drug: thiotepa
Drug: vincristine sulfate
Procedure: bone marrow ablation with stem cell support
Procedure: peripheral blood stem cell transplantation
Radiation: radiation therapy

First Posted Date: 2004-05-25

Last Posted Date: 2014-07-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 25

Registration Number: NCT00003846

Locations: 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States
🇺🇸
Children's Hospital of Orange County, Orange, California, United States

and more 10 locations

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Phase 3

Completed

Conditions: Central Nervous System Tumors
Brain Tumors

Interventions: Biological: filgrastim
Drug: cisplatin
Drug: cyclophosphamide
Drug: lomustine
Drug: mesna
Drug: vincristine sulfate
Radiation: low-LET electron therapy
Radiation: low-LET photon therapy

First Posted Date: 2004-05-24

Last Posted Date: 2014-08-01

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 421

Registration Number: NCT00002875

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 38 locations

Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia

Phase 1

Completed

Conditions: Leukemia

Interventions: Biological: filgrastim
Drug: asparaginase
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: melphalan
Drug: thioguanine
Procedure: peripheral blood stem cell transplantation

First Posted Date: 2004-05-20

Last Posted Date: 2014-07-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 35

Registration Number: NCT00004056

Locations: 🇺🇸
University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 17 locations

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Active, not recruiting

Conditions: Childhood Malignant Neoplasm

Interventions: Other: Laboratory Biomarker Analysis
Other: Questionnaire Administration

First Posted Date: 2004-05-19

Last Posted Date: 2025-03-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 3885

Registration Number: NCT00082745

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Arkansas Children's Hospital, Little Rock, Arkansas, United States

and more 153 locations

hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Phase 2

Completed

Conditions: Neuroblastoma

Interventions: Biological: hu14.18-Interleukin-2 fusion protein

First Posted Date: 2004-05-19

Last Posted Date: 2015-02-12

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 39

Registration Number: NCT00082758

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

and more 78 locations

Temozolomide in Treating Young Patients With Refractory or Recurrent Leukemia

Phase 1

Completed

Conditions: Leukemia

Interventions: Drug: temozolomide

First Posted Date: 2004-05-17

Last Posted Date: 2014-02-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 16

Registration Number: NCT00083070

Locations: 🇺🇸
Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States
🇺🇸
Indiana University Cancer Center, Indianapolis, Indiana, United States
🇺🇸
Fairview University Medical Center - University Campus, Minneapolis, Minnesota, United States

and more 13 locations

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors

Phase 2

Completed

Conditions: Desmoid Tumor

Interventions: Drug: methotrexate
Drug: vinblastine sulfate

First Posted Date: 2004-04-30

Last Posted Date: 2014-07-25

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 28

Registration Number: NCT00003019

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 36 locations

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