Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia

Phase 3

Completed

Conditions: Leukemia
Lymphoma

Interventions: Biological: filgrastim
Drug: cyclophosphamide
Drug: cytarabine
Drug: dexamethasone
Drug: doxorubicin hydrochloride
Drug: leucovorin calcium
Drug: etoposide
Drug: methotrexate
Drug: ifosfamide
Drug: vincristine sulfate

First Posted Date: 2003-05-21

Last Posted Date: 2013-08-21

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 83

Registration Number: NCT00005977

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States

and more 116 locations

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

Phase 2

Completed

Conditions: Brain Tumors
Central Nervous System Tumors
Neuroblastoma

Interventions: Biological: filgrastim
Drug: carboplatin
Drug: cisplatin
Drug: cyclophosphamide
Drug: vincristine sulfate
Procedure: adjuvant therapy
Radiation: radiation therapy

First Posted Date: 2003-05-19

Last Posted Date: 2013-08-23

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 168

Registration Number: NCT00003203

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 35 locations

Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell Lymphoma

Phase 3

Completed

Conditions: Lymphoma

Interventions: Drug: doxorubicin hydrochloride
Drug: mercaptopurine
Drug: methotrexate
Drug: prednisone
Drug: vincristine sulfate
Drug: vinblastine sulfate

First Posted Date: 2003-05-07

Last Posted Date: 2014-09-22

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 129

Registration Number: NCT00059839

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 156 locations

Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia

Not Applicable

Completed

Conditions: Leukemia

First Posted Date: 2003-05-02

Last Posted Date: 2014-08-07

Lead Sponsor: Children's Oncology Group

Registration Number: NCT00003933

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 38 locations

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Phase 1

Completed

Conditions: Cancer

Interventions: Biological: recombinant human thrombopoietin
Drug: carboplatin
Drug: etoposide
Drug: ifosfamide
Biological: G-CSF

First Posted Date: 2003-04-18

Last Posted Date: 2014-07-24

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 16

Registration Number: NCT00003597

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 21 locations

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Phase 2

Completed

Conditions: Childhood Immunoblastic Large Cell Lymphoma
Childhood Diffuse Large Cell Lymphoma
Stage I Childhood Small Noncleaved Cell Lymphoma
Stage II Childhood Large Cell Lymphoma
Stage II Childhood Small Noncleaved Cell Lymphoma
Stage IV Childhood Small Noncleaved Cell Lymphoma
Stage I Childhood Large Cell Lymphoma
Stage III Childhood Large Cell Lymphoma
Stage IV Childhood Large Cell Lymphoma
Untreated Childhood Acute Lymphoblastic Leukemia

Interventions: Drug: doxorubicin hydrochloride
Drug: cyclophosphamide
Drug: methotrexate
Drug: leucovorin calcium
Drug: rasburicase
Drug: prednisone
Drug: methylprednisolone
Biological: filgrastim
Biological: rituximab
Drug: cytarabine
Drug: etoposide
Drug: vincristine sulfate
Drug: hydrocortisone sodium succinate
Other: laboratory biomarker analysis

First Posted Date: 2003-04-09

Last Posted Date: 2014-09-19

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 97

Registration Number: NCT00057811

Locations: 🇺🇸
Children's Oncology Group, Arcadia, California, United States

Study of the Physical and Emotional Needs of Parents Caring for Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia

Not Applicable

Completed

Conditions: Leukemia

Interventions: Other: questionnaire administration

First Posted Date: 2003-03-07

Last Posted Date: 2015-05-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 172

Registration Number: NCT00056069

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States

and more 118 locations

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

Phase 3

Completed

Conditions: Ovarian Embryonal Carcinoma
Stage IIC Ovarian Germ Cell Tumor
Stage III Malignant Testicular Germ Cell Tumor
Stage IIIA Ovarian Germ Cell Tumor
Childhood Embryonal Tumor
Childhood Extracranial Germ Cell Tumor
Childhood Extragonadal Germ Cell Tumor
Childhood Malignant Testicular Germ Cell Tumor
Childhood Teratoma
Ovarian Yolk Sac Tumor

Interventions: Procedure: conventional surgery
Drug: cisplatin
Drug: etoposide
Biological: bleomycin sulfate
Other: laboratory biomarker analysis

First Posted Date: 2003-01-28

Last Posted Date: 2021-07-13

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 302

Registration Number: NCT00053352

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Childrens Hospital, Phoenix, Arizona, United States
🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 123 locations

Irinotecan in Treating Children With Refractory Solid Tumors

Phase 2

Completed

Conditions: Childhood Central Nervous System Germ Cell Tumor
Childhood Choroid Plexus Tumor
Childhood Craniopharyngioma
Childhood Grade I Meningioma
Childhood Grade II Meningioma
Childhood Grade III Meningioma
Childhood Infratentorial Ependymoma
Childhood Oligodendroglioma
Childhood Supratentorial Ependymoma
Previously Treated Childhood Rhabdomyosarcoma

Interventions: Drug: irinotecan hydrochloride

First Posted Date: 2003-01-28

Last Posted Date: 2013-06-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 181

Registration Number: NCT00004078

Locations: 🇺🇸
Children's Oncology Group, Arcadia, California, United States

Combination Chemotherapy in Treating Children With Refractory or Relapsed Hodgkin's Lymphoma

Phase 2

Completed

Conditions: Lymphoma

Interventions: Biological: filgrastim
Drug: ifosfamide
Drug: vinorelbine tartrate

First Posted Date: 2003-01-27

Last Posted Date: 2013-07-26

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 66

Registration Number: NCT00006760

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 111 locations

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Children's Oncology Group

Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell Lymphoma

Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Study of the Physical and Emotional Needs of Parents Caring for Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

Irinotecan in Treating Children With Refractory Solid Tumors

Combination Chemotherapy in Treating Children With Refractory or Relapsed Hodgkin's Lymphoma